CelLock TM: an innovative standardized cell-block preparation procedure

IF 0.6 4区生物学 Q4 CELL BIOLOGY

Journal of Histotechnology Pub Date : 2022-03-10 DOI:10.1080/01478885.2022.2046683

Clifford M. Chapman

引用次数: 0

Abstract

ABSTRACT The CelLock™ procedure kit is used to collect and prepare cellular specimens such as fine needle aspirates (FNA), cytology specimens, cultured cells, small tissue biopsies, and samples with scant tissue fragments or cells into a paraffin cell-block. This cell-block can be used for subsequent microtomy and staining using hematoxylin and eosin (H&E), special stains, immunohistochemistry (IHC), and applicable molecular techniques such as in situ hybridization (ISH). CelLock is a standardized method that provides optimal receipt, preservation, preparation, and processing of cell-blocks which, contain virtually all of the submitted specimens and are able to be embedded and sectioned in a reproducible fashion. The specimen contained within the cell-block is preserved such that all the cellular protein and genetic information is available for histological and ancillary testing.

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CelLock TM：一种创新的标准化细胞块制备程序

摘要CelLock™ 程序试剂盒用于收集和制备细胞样本，如细针抽吸物（FNA）、细胞学样本、培养细胞、小组织活检，以及将组织碎片或细胞稀少的样本制成石蜡细胞块。该细胞块可用于随后的切片和染色，使用苏木精和伊红（H&E）、特殊染色、免疫组织化学（IHC）和适用的分子技术，如原位杂交（ISH）。CelLock是一种标准化方法，可提供细胞块的最佳接收、保存、制备和处理，细胞块几乎包含所有提交的样本，并能够以可复制的方式嵌入和切片。包含在细胞块内的标本被保存，使得所有细胞蛋白质和遗传信息可用于组织学和辅助测试。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Histotechnology 生物-细胞生物学

CiteScore

2.60

自引率

9.10%

发文量

审稿时长

>12 weeks

期刊介绍： The official journal of the National Society for Histotechnology, Journal of Histotechnology, aims to advance the understanding of complex biological systems and improve patient care by applying histotechniques to diagnose, prevent and treat diseases. Journal of Histotechnology is concerned with educating practitioners and researchers from diverse disciplines about the methods used to prepare tissues and cell types, from all species, for microscopic examination. This is especially relevant to Histotechnicians. Journal of Histotechnology welcomes research addressing new, improved, or traditional techniques for tissue and cell preparation. This includes review articles, original articles, technical notes, case studies, advances in technology, and letters to editors. Topics may include, but are not limited to, discussion of clinical, veterinary, and research histopathology.