Bioethics and Psoriasis

H. Allen, R. Allawh, L. Ogrich, N. Jariwala, Erum N Ilyas
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Abstract

We have presented the clinical, epidemiological, microbiological, pathological, immunopathological, serological, and therapeutic studies showing how the streptococcus may be strongly linked to psoriasis. With this as background, we have presented three ethical arguments that are cogent for psoriasis. First, this microbial “pathogen” theory is both ignored and overlooked even with the abundance of evidence supporting it. That being the case, current treatments, consequently, are aimed not at the onset of the disease, but much later in the pathogenic cascade. Last, the continued use of “biologics” or costly immunosuppressives, which are not curative, presents bioethical challenges. We consider psoriasis a sequela of streptococcal infection similar to rheumatic fever, where treatment, at the earliest stages of the disease, has resulted in its disappearance.
生物伦理学与牛皮癣
我们已经提出了临床、流行病学、微生物学、病理学、免疫病理学、血清学和治疗研究,表明链球菌可能与牛皮癣密切相关。在此背景下,我们提出了三个对牛皮癣有说服力的伦理论点。首先,即使有大量证据支持,这种微生物“病原体”理论也被忽视了。在这种情况下,目前的治疗方法,因此,不是针对疾病的开始,而是在致病级联的后期。最后,继续使用“生物制剂”或昂贵的免疫抑制剂,这不是治疗,提出了生物伦理挑战。我们认为牛皮癣是链球菌感染的后遗症,类似于风湿热,在疾病的早期阶段,治疗已导致其消失。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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