Cross-reacting surface proteins between different Escherichia coli O157:H7 strains and their immune responses in animal models

Abstract

Enterohemorrhagic Escherichia. coli O157:H7 is one of the significant causes of food and waterborne illness in the developed nations across the globe. Transmission of the disease mainly occurs via the consumption of contaminated food, water and person to persontransmission1. Clinical spectrum of the disease includes watery diarrhea, bloody diarrhea, hemorrhagic colitis and life-threatening hemolytic uremic syndrome (HUS), which may develop in the people of all age groups.