Gut-brain axis and alcohol dependence: Exploring the role of Psychobiotics in treatment

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Abstract

Chronic alcohol use adversely impacts the gut, including increased intestinal permeability and alteration in gut microbiota. Recent research has pointed to the association between alteration in gut microbiota and the induction of alcohol cravings. The term “psychobiotics” has been coined for microorganisms that, when ingested in sufficient amounts, may have beneficial effects on psychiatric illnesses. This letter to the editor highlights the possible mechanism underlying the therapeutic role of psychobiotics in addictive disorders and urges the scientific community to direct research focus on this avenue.
肠脑轴与酒精依赖:探讨精神生物疗法在治疗中的作用
长期饮酒对肠道有不利影响,包括肠道通透性增加和肠道微生物群改变。最近的研究指出,肠道微生物群的改变与酒精渴望的诱导之间存在关联。“精神生物制剂”一词是指摄入足够量的微生物,这些微生物可能对精神疾病有有益的影响。这封致编辑的信强调了精神生物制剂在成瘾性疾病中治疗作用的可能机制,并敦促科学界将研究重点放在这一途径上。
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