Pharmacological Attributes of Hesperidin

IF 0.6 Q4 INTEGRATIVE & COMPLEMENTARY MEDICINE

Current Traditional Medicine Pub Date : 2023-08-22 DOI:10.2174/2215083810666230822113623

Y. Siddique, Iqra Subhan

引用次数: 0

Abstract

Hesperidin is a major flavonoid in sweet oranges and lemons. Aglycone form of hesperidin i.e., hesperetin, and their various derivatives possess significant potential as therapeutic agents for a wide range of diseases and disorders. No signs of toxicity have been observed with the normal intake of hesperidin or related compounds. Hesperidin has been reported to possess a wide range of pharmacological properties, which includes antioxidant, anti-viral, anticancer, antidiabetic, analgesic, organ protective, neuroprotective, antihypertensive, and cardioprotective effects. This needs to be effectively studied at the clinical level so as to firmly establish the usefulness of these compounds in the treatment or prevention of disease in humans. This paper reviews various aspects of hesperidin, including their chemistry, biosynthesis, and bioactivity.

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橙皮苷的药理特性

橙皮苷是甜橙和柠檬中的一种主要黄酮类化合物。橙皮苷的甘醇形式，即橙皮素及其各种衍生物，作为一系列疾病和病症的治疗剂具有巨大的潜力。在正常摄入橙皮苷或相关化合物的情况下，未观察到毒性迹象。据报道，橙皮苷具有广泛的药理特性，包括抗氧化、抗病毒、抗癌、抗糖尿病、镇痛、器官保护、神经保护、降压和心脏保护作用。这需要在临床水平上进行有效的研究，以便牢固地确定这些化合物在治疗或预防人类疾病中的有用性。本文对橙皮苷的化学、生物合成和生物活性等方面进行了综述。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Current Traditional Medicine INTEGRATIVE & COMPLEMENTARY MEDICINE-

CiteScore

1.40

自引率

0.00%

发文量

期刊介绍： Current Traditional Medicine covers all the aspects of the modernization and standardization research on traditional medicine of the world, e.g. chemistry, pharmacology, molecular mechanism, systems biology, proteomics, genomics, metabolomics, safety, quality control, clinical studies of traditional Chinese, Ayurvedic, Unani, Arabic and other ethnomedicine. Each issue contains updated comprehensive in-depth/mini reviews along with high quality original experimental research articles. Current Traditional Medicine is a leading and important international peer-reviewed journal reflecting the current outstanding scientific research progresses of the global traditional, indigenous, folk and ethnologic medicine. It provides a bridge connected the tradition medicine system to the modern life science with the efforts of top scientists, as well as a resource to pursuit the solutions for the existing common issues in the traditional medicine.