Perceived Stress Predicts Drug Use in Transgender Women: The Mediating Role of Loneliness.

IF 4.6 Q2 MATERIALS SCIENCE, BIOMATERIALS

ACS Applied Bio Materials Pub Date : 2024-10-09 eCollection Date: 2024-10-01 DOI:10.1089/trgh.2022.0121

Lulu Xu, Ruijie Chang, Yingjie Chen, Danni Xia, Chen Xu, Xiaoyue Yu, Hui Chen, Rongxi Wang, Yujie Liu, Shangbin Liu, Xin Ge, Tiecheng Ma, Ying Wang, Yong Cai

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引用次数: 0

Abstract

Purpose: Drug use is quite common in transgender women, but the mechanisms of the drug use remain unclear. The purpose of this study was to investigate the mediating role of loneliness in perceived stress and the drug use among transgender women.

Methods: A cross-sectional survey was conducted from April to September 2018 in Shenyang and Kunming, China, among 247 transgender women. Chinese Perceived Stress Scale, the Chinese version of 8-item UCLA Loneliness Scale, a drug use questionnaire, and a demographic characteristic questionnaire were included in the survey. Descriptive analysis, logistic regression, and mediation analysis were done using SPSS Statistics version 26.0 and Mplus version 8.3.

Results: The mean age of transgender women in the study was 33.04 years (standard deviation=8.14). Around 33.20% (n=82) of transgender women reported ever using one kind of drugs, the most commonly used drugs were rush (79.20%), ice (8.50%), and 5-MeO-DIPT (8.50%). Univariate logistic regression showed that perceived stress (odds ratio [OR]=1.73, 95% bootstrap confidence intervals [CI]=1.27-2.36) and loneliness (OR=1.62, 95% CI=1.23-2.13) had a significant association with drug use, all p [ps] <0.01. The effect of perceived stress on drug use was partially mediated by feeling of loneliness (estimate=0.09, standard error=0.04, p<0.05), the mediating effect (0.09) accounted for 27.27% of the total effect (0.33).

Conclusion: Perceived stress can positively predict drug use. Loneliness plays an important role in drug use among transgender women.

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感知压力预测跨性别女性的药物使用：孤独感的中介作用

目的：变性女性使用毒品的现象相当普遍，但使用毒品的机制仍不清楚。本研究旨在探讨孤独感在变性女性感知压力和吸毒中的中介作用：2018年4月至9月，在中国沈阳和昆明对247名跨性别女性进行了横断面调查。调查包括中文版感知压力量表、中文版8项UCLA孤独感量表、药物使用问卷和人口学特征问卷。使用 26.0 版 SPSS 统计软件和 8.3 版 Mplus 进行了描述性分析、逻辑回归和中介分析：研究中变性女性的平均年龄为 33.04 岁（标准差=8.14）。约有 33.20%（n=82）的变性女性表示曾经使用过一种药物，最常用的药物是急支（79.20%）、冰（8.50%）和 5-甲基-O-二羟基甲苯（8.50%）。单变量逻辑回归显示，感知到的压力（几率比[OR]=1.73，95%自回归置信区间[CI]=1.27-2.36）和孤独感（OR=1.62，95% CI=1.23-2.13）与吸毒有显著关联，所有数据均为 p [ps] p结论：感知到的压力可以正面预测吸毒情况。孤独感在变性女性吸毒中起着重要作用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

ACS Applied Bio Materials Chemistry-Chemistry (all)

CiteScore

9.40

自引率

2.10%

发文量

464

期刊介绍： ACS Applied Bio Materials is an interdisciplinary journal publishing original research covering all aspects of biomaterials and biointerfaces including and beyond the traditional biosensing, biomedical and therapeutic applications. The journal is devoted to reports of new and original experimental and theoretical research of an applied nature that integrates knowledge in the areas of materials, engineering, physics, bioscience, and chemistry into important bio applications. The journal is specifically interested in work that addresses the relationship between structure and function and assesses the stability and degradation of materials under relevant environmental and biological conditions.