Thin membrane with biomimetic hexagonal patterned surface for guided bone regeneration

Q4 Chemistry

International Journal of Nano and Biomaterials Pub Date : 2018-09-27 DOI:10.1504/IJNBM.2018.10016280

Anurag Satpathy, R. Mohanty, T. Rautray

引用次数: 0

Abstract

Polymeric membranes used as a barrier in guided tissue regeneration have undergone several modifications for improved structural, handling and biological properties. Biomaterial surface characteristics are critical in regulating cell function. Physicochemical signals from the substrate surfaces stimulate cell behaviour. This paper focuses on fabrication of biodegradable barrier membrane with hexagonal patterned surface for guided tissue regeneration. Hexagonal patterned surfaces were obtained during solvent casting of chitosan solution using a novel method. Obtained barrier membranes were analysed under stereo and electron microscopy and were assessed for their surface roughness. The hexagonal patterned surface barrier membranes had a significantly higher surface roughness (p < 0.001).

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仿生六边形表面薄膜引导骨再生

在引导组织再生中用作屏障的聚合物膜经过了多次修改，以改善结构、操作和生物性能。生物材料表面特性对调节细胞功能至关重要。来自基质表面的物理化学信号刺激细胞行为。本文重点研究了一种具有六边形图案表面的可生物降解屏障膜的制备，用于引导组织再生。采用一种新的方法在壳聚糖溶液的溶剂浇铸过程中获得了六边形图案的表面。在立体显微镜和电子显微镜下分析获得的阻隔膜，并评估其表面粗糙度。六边形图案的表面阻挡膜具有显著更高的表面粗糙度（p＜0.001）。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

International Journal of Nano and Biomaterials Chemistry-Physical and Theoretical Chemistry

CiteScore

1.20

自引率

0.00%

发文量

期刊介绍： In recent years, frontiers of research in engineering, science and technology have been driven by developments in nanomaterials, encompassing a diverse range of disciplines such as materials science, biomedical engineering, nanomedicine and biology, manufacturing technology, biotechnology, nanotechnology, and nanoelectronics. IJNBM provides an interdisciplinary vehicle covering these fields. Advanced materials inspired by biological systems and processes are likely to influence the development of novel technologies for a wide variety of applications from vaccines to artificial tissues and organs to quantum computers. Topics covered include Nanostructured materials/surfaces/interfaces Synthesis of nanostructures Biological/biomedical materials Artificial organs/tissues Tissue engineering Bioengineering materials Medical devices Functional/structural nanomaterials Carbon-based materials Nanomaterials characterisation Novel applications of nanomaterials Modelling of behaviour of nanomaterials Nanomaterials for biomedical applications Biological response to nanomaterials.