Potential effect of probiotics in the treatment of breast cancer

IF 3.1 Q2 ONCOLOGY

Oncology Reviews Pub Date : 2019-07-22 DOI:10.4081/oncol.2019.422

L. Mendoza

引用次数: 50

Abstract

Breast cancer is one of the most important causes of cancerrelated morbidity and mortality in the world. Probiotics, as functional food, have the potential to act against breast cancer, as evidenced by cell-based and animal model experiments. Probiotic may be useful in prevention or treatment of breast cancer by modulating the gastrointestinal bacteria and the systemic immune system. However, large-scale clinical trials and intensive research are mandatory to confirm the in vitro and in vivo results and exploring the probiotics-related metabolic, immune, and molecular mechanisms in breast cancer. This current review summarizes the available data related to probiotics and their potential role in the treatment of breast cancer.

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益生菌治疗癌症的潜在疗效

癌症是世界上与癌症相关的发病率和死亡率的最重要原因之一。益生菌作为功能性食物，具有对抗癌症的潜力，基于细胞和动物模型的实验证明了这一点。益生菌可以通过调节胃肠道细菌和全身免疫系统来预防或治疗癌症。然而，大规模的临床试验和深入的研究是必须的，以确认体外和体内结果，并探索益生菌相关的代谢、免疫和分子机制在乳腺癌症。本综述总结了与益生菌相关的现有数据及其在癌症治疗中的潜在作用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Oncology Reviews ONCOLOGY-

CiteScore

6.30

自引率

0.00%

发文量

审稿时长

9 weeks

期刊介绍： Oncology Reviews is a quarterly peer-reviewed, international journal that publishes authoritative state-of-the-art reviews on preclinical and clinical aspects of oncology. The journal will provide up-to-date information on the latest achievements in different fields of oncology for both practising clinicians and basic researchers. Oncology Reviews aims at being international in scope and readership, as reflected also by its Editorial Board, gathering the world leading experts in both pre-clinical research and everyday clinical practice. The journal is open for publication of supplements, monothematic issues and for publishing abstracts of scientific meetings; conditions can be obtained from the Editor-in-Chief or the publisher.