Blood Characteristics in Dogs During Treatment of Babesiosis Using Transfusion of Cryopreserved Erythrocytes

Q4 Medicine
Оlha Denysova, G. Zhegunov, T. Yakimenko, N. Hladka, V. Prichodchenko, Olha Bobrutska
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引用次数: 0

Abstract

Babesiosis is one of the most common protozoan diseases in dogs, which in the absence of the necessary veterinary care often leads to the animal death. The changes of hematological parameters in dogs during complex treatment of babesiosis and transfusion of cryopreserved erythrocytes were evaluated in the research. Erythrocytes were frozen using 20% DMSO by immersion into liquid nitrogen. Transfusion of cryopreserved erythrocytes together with antiparasitic chemotherapy has been shown to promote rapid recovery of hematological parameters of animal blood (hemoglobin, hematocrit and erythrocyte counts), as well as improves their well-being, promotes faster recovery. Cryopreserved with DMSO erythrocytes can be recommended for long-term storage of blood at cryobanks.
输血冷冻红细胞治疗巴贝斯虫病期间狗的血液特征
巴贝斯虫病是犬类最常见的原生动物疾病之一,在缺乏必要的兽医护理的情况下,往往会导致动物死亡。本研究评价了犬在巴贝斯虫病综合治疗和低温红细胞输注过程中血液学参数的变化。红细胞用20%二甲基亚砜浸泡在液氮中冷冻。输血低温保存的红细胞与抗寄生虫化疗已被证明可以促进动物血液的血液学参数(血红蛋白、红细胞压积和红细胞计数)的快速恢复,并改善它们的健康,促进更快的恢复。低温保存与DMSO红细胞可以推荐长期储存的血液在冷冻银行。
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来源期刊
Problems of Cryobiology and Cryomedicine
Problems of Cryobiology and Cryomedicine Medicine-Medicine (miscellaneous)
CiteScore
0.60
自引率
0.00%
发文量
9
期刊介绍: The Journal publishes the reviews and original papers on cryobiological and cryomedical research, in particular the elucidation of mechanisms of injuries occurring in biological objects and caused by the influence of low and ultra low temperatures; natural resistance of biologicals to cold and their recovery post effect; the development of effective methods of cryoprotection and technology of storage of biological resources under hypothermic and ultra low temperatures, application of hypothermia, cryotherapy and cryopreserved biologicals for treating various pathologies; cell and tissue based therapies and other issues of low-temperature biology and medicine, as well as development of devices and equipment for low temperature biology and medicine. The journal covers all topics related to low temperature biology, medicine and engineering. These include but are not limited to: low temperature storage of biologicals (human, animal or plant cells, tissues, and organs), including preparation for storage, thawing/warming, cell and tissue culturing etc. response of biologicals to low temperature; cold adaptation of animals and plants; utilisation of low temperature in medicine; experimental and clinical transplantation, cell and tissue based therapies; developing of cryobiological and cryomedical devices; organisation and functioning of low temperature banks etc.
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