Colorectal liver metastases: Resect, ablate, or embolize

IF 0.4 Q4 SURGERY

Seminars in Colon and Rectal Surgery Pub Date : 2023-09-01 DOI:10.1016/j.scrs.2023.100968

Natasha Leigh MD, Dominic E. Sanford MD

引用次数: 0

Abstract

The management of colorectal liver metastases (CRLM) is complex and should be individualized to each patient. Resectable CRLM benefit from surgical resection, preferably minimally invasive and parenchymal sparing, when feasible. Ablation is a viable alternative. Chemotherapy in this setting is potentially indicated in select patients, however, it has a clear role in unresectable CRLM. Newer locoregional therapies may benefit some unresectable CRLM with resistance to chemotherapy. Liver transplantation, a new therapy on the horizon for unresectable disease, has encouraging preliminary long-term survival outcomes for carefully selected patients.

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结直肠癌肝转移：切除、消融或栓塞

结直肠肝转移(CRLM)的治疗是复杂的，应该个体化治疗。可切除的CRLM受益于手术切除，如果可行，最好是微创和保留实质。消融是一种可行的替代方法。然而，在这种情况下，化疗在不可切除的CRLM中有明确的作用。较新的局部治疗方法可能使一些对化疗有耐药性的不可切除的CRLM受益。肝移植是一种治疗不可切除疾病的新疗法，对于精心挑选的患者，初步的长期生存结果令人鼓舞。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Seminars in Colon and Rectal Surgery SURGERY-

CiteScore

0.60

自引率

0.00%

发文量

期刊介绍： Seminars in Colon and Rectal Surgery offers a comprehensive and coordinated review of a single, timely topic related to the diagnosis and treatment of proctologic diseases. Each issue is an organized compendium of practical information that serves as a lasting reference for colorectal surgeons, general surgeons, surgeons in training and their colleagues in medicine with an interest in colorectal disorders.