" The Use Of Stem Cells In The Surgical Treatment Of Cleft Palate "

Caroline C. McCall, V. Gallicchio
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Abstract

Mesenchymal stem cells, pluripotent and differentiable cells found naturally within bone marrow, adipose tissue, the blood of the umbilical cord, and dental pulp have the capability to transform the field of oral surgery. With the capability to differentiate into different types of tissue, stem cells are currently being studied as an alternative to autologous bone grafting for treatment of cleft palate in young children. The long-standing treatment of autologous bone-grafting, while very effective, has many risks associated with it such as graft rejection, post-operative morbidity, and long recovery time. The harvesting and transplantation of stem cells using bio-compatible scaffolding that will differentiate and form new bone tissue is the future of valvuloplasty protocol in the field of oral surgery. This paper will investigate the way in which this treatment will be performed, the advantages and risks of stem cell therapy, the future applications, as well as the issue of global accessibility to innovative treatment such as this.
干细胞在腭裂手术治疗中的应用
骨髓、脂肪组织、脐带血液和牙髓中天然存在的间充质干细胞、多能和可分化细胞具有改变口腔外科领域的能力。干细胞具有分化成不同类型组织的能力,目前正在研究作为自体骨移植治疗幼儿腭裂的替代方法。自体骨移植的长期治疗虽然非常有效,但也存在许多风险,如移植排斥反应、术后发病率和恢复时间长。利用生物相容性支架收集和移植干细胞,分化并形成新的骨组织,是口腔外科瓣膜成形术的未来。本文将探讨这种治疗的实施方式,干细胞治疗的优势和风险,未来的应用,以及全球获得这种创新治疗的问题。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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