Cierre de orejuela izquierda frente a ACOD en pacientes mayores: an�lisis con emparejamiento por puntuaci�n de propensi�n

IF 1.2 Q3 CARDIAC & CARDIOVASCULAR SYSTEMS

REC Interventional Cardiology Pub Date : 2022-10-13 DOI:10.24875/recic.m22000316

Berenice Caneiro-Queija, Rodrigo Estévez-Loureiro, Sergio Raposeiras-Roubín, Emad Abu-Assi, Rocío González-Ferreiro, I. Cruz-González, Alejandro Diego-Nieto, Antonio A. de Miguel-Castro, Guillermo Bastos-Fernández, J. A. Baz-Alonso, Guilles O’Hara, Josep Rodés-Cabau y, Andrés Íñiguez-Romo

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Abstract

Introduction and objectives: Information comparing left atrial appendage closure (LAAC) to direct oral anticoagulation (DOAC) therapy is scarce. Our aim is to compare the clinical outcomes between LAAC and DOACs on an elderly population (> 80 years of age). Methods: We retrospectively collected 1144 octogenarian patients with atrial fibrillation from 3 different tertiary hospitals. A total of 970 patients received DOACs and 174 patients were treated with LAAC. At baseline, both groups had similar cardiovascular risk factors. The LAAC group had more history of bleeding, anemia or previous cancer. We conducted a propensity score matching study and obtained 2 different paired groups of 58 patients with similar baseline risk factors, comorbidities, and risk scores who received DOACs or were treated with LAAC. The outcomes of the therapeutic strategy used (DOACs or LAAC) were assessed using the Cox regression analysis. ARTICLE IN PRESS Cómo citar este artículo: Caneiro-Queija B, et al. Cierre de orejuela izquierda frente a ACOD en pacientes mayores: análisis con emparejamiento por puntuación de propensión. REC Interv Cardiol. 2022. https://doi.org/10.24875/RECIC.M22000316 2 B. Caneiro-Queija et al. REC Interv Cardiol. 20XX;XX(X):XX-XX

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老年患者左耳关闭与ACOD：按倾向评分配对的分析

引言和目的：比较左心耳封堵术（LAAC）和直接口服抗凝治疗（DOAC）的信息很少。我们的目的是比较LAAC和DOAC在老年人群（>80岁）中的临床结果。方法：我们回顾性地收集了来自3家不同的三级医院的1144名八旬心房颤动患者。共有970名患者接受DOAC治疗，174名患者接受LAAC治疗。在基线时，两组的心血管危险因素相似。LAAC组有更多出血、贫血或既往癌症病史。我们进行了一项倾向评分匹配研究，获得了两组不同的配对患者，每组58名，基线风险因素、合并症和风险评分相似，接受DOAC或接受LAAC治疗的患者。使用Cox回归分析评估所用治疗策略（DOAC或LAAC）的结果。新闻中心的文章：Caneiro Queija B等人。REC介入心脏病学。2022https://doi.org/10.24875/RECIC.M220003162 B.Caneiro Queija等人REC Interv Cardiol。20XX；XX（X）:XX-XX

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