Brucella infection in children: Evaluation of 148 pediatric patients

Journal of Clinical and Analytical Medicine Pub Date : 2019-01-01 DOI:10.4328/JCAM.5956

Ö. Gündeşlioğlu

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引用次数: 3

Abstract

DOI: 10.4328/JCAM.5956 Received: 28.06.2018 Accepted: 28.07.2018 Published Online: 29.07.2018 Printed: 01.01.2019 J Clin Anal Med 2019;10(1): 99-103 Corresponding Author: Özlem Özgür Gündeşlioğlu, Deparment of Pediatric Division of Pediatric Infectious Diseases, Faculty of Medicine, Cukurova University, Adana, Turkey. GSM: +905055677801 E-Mail:ozlemozgur1978@yahoo.com ORCID ID: 0000-0003-2202-7645 Abstract Aim: Brucellosis a worldwide infectious zoonotic disease. This study was aimed to evaluate the clinical, demographic characteristics, complications, treatment and follow-up results of pediatric patients diagnosed with brucellosis. Material and Method: The medical records of 148 pediatric patients who were diagnosed with brucellosis were studied retrospectively. Results: Sixty-one female (41.2%), 87 male (58.8%), in total 148 pediatric patients who were diagnosed with brucellosis were included in the study. Among the patients, 64.1% had a history of consuming fresh cheese, 4.1% had a history of consuming raw milk and 16.9% had a history of keeping a Brucella diagnosed animal at home. Brucella history rate in the family members of the patients was determined as 39.2%; and 12.8% of the patients included in the study were asymptomatic. The most common complaint of the patients who were symptomatic was fever (59.5%) followed by arthralgias (41.2%) and leg pain (38.5%). All patients were subjected to standard tube agglutination test and blood culture was taken from 93 patients. B. melitensis in blood culture was positive in 72% of the patients. Osteoarticular involvement developed in 12.1% of the patients; and 1.3% of the patients developed relapses after the end of the treatment. Discussion: Brucellosis is still an endemic disease in Turkey. Brucella can infect all organs and tissues and is a major cause of morbidity. The use of more than one antibiotic in the treatment and long treatment duration reduces patient compliance; thus, close follow-up of the patients is important.

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儿童布鲁氏菌感染:148例儿科患者的评价

DOI:10.4328/JCAM.5956接收日期：2018年6月28日接受日期：2018月7日在线发布日期：2018年年7月29日印刷日期：2019年1月1日《临床分析医学杂志》；10（1）：99-103通讯作者：ÖzlemÖzgür Gündeşlioğlu，土耳其阿达纳库库罗瓦大学医学院儿科传染病科主任。GSM:+990555677801电子邮箱：ozlemozgur1978@yahoo.comORCID ID:0000-0003-2202-7645摘要目的：布鲁氏菌病是一种全球性的人畜共患传染病。本研究旨在评估诊断为布鲁氏菌病的儿童患者的临床、人口学特征、并发症、治疗和随访结果。材料与方法：回顾性分析148例诊断为布鲁氏菌病患儿的病历资料。结果：在总共148名被诊断为布鲁氏菌病的儿科患者中，61名女性（41.2%）、87名男性（58.8%）被纳入研究。在这些患者中，64.1%有食用新鲜奶酪的历史，4.1%有食用生牛奶的历史，16.9%有在家饲养布鲁氏菌诊断动物的历史。患者家属布鲁氏菌史检出率为39.2%；12.8%的患者无症状。有症状的患者最常见的主诉是发烧（59.5%），其次是关节痛（41.2%）和腿痛（38.5%）。所有患者都接受了标准试管凝集试验，并对93名患者进行了血液培养。血培养阳性率为72%。12.1%的患者出现骨关节受累；1.3%的患者在治疗结束后出现复发。讨论：布鲁氏菌病仍是土耳其的地方病。布鲁氏菌可感染所有器官和组织，是发病的主要原因。在治疗中使用一种以上的抗生素，并且治疗持续时间长，会降低患者的依从性；因此，对患者进行密切的随访是很重要的。

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Journal of Clinical and Analytical Medicine MEDICINE, GENERAL & INTERNAL-

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期刊介绍： The Annals of Clinical and Analytical Medicine is an international open-access journal containing peer-reviewed high-quality articles on clinical medicine in the areas of all research study types, reviews, and case reports. Our journal has become an important platform with the help of language support services, which make it easier for writers who have English as their second language to share their clinical experiences with the world.