Habitable Underwater Hyperbaric Facilities: Respiratory Balance in the Human Organism During Adapting to Saturation Nitrogen-Oxygen Hyperbaria

IF 0.2 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH
S. Gulyar, Yu. M. Barats
{"title":"Habitable Underwater Hyperbaric Facilities: Respiratory Balance in the Human Organism During Adapting to Saturation Nitrogen-Oxygen Hyperbaria","authors":"S. Gulyar, Yu. M. Barats","doi":"10.2478/phr-2019-0014","DOIUrl":null,"url":null,"abstract":"Abstract There were evaluated responses of the respiratory system to changes in the variables of the external environment under increased pressure. To the model of professional underwater human activity underwater served the conditions of full saturation in compressed air or nitrogen-oxygen gas mixtures. Technical devices were presented by a number of underwater laboratories, mounted at the bottom (Ikhtiander-66, 67 and 68), hyperbaric chambers, submersible drilling rigs (Bur-1 and 2), and an autonomous diving Ikhtiander-2 for a long stay in the water. Studies of respiratory gases mass transport conditions in man showed than within the pressure range of 0.25-1.1 MPa at density of moderate hyperoxic and nitrogen-helio-oxygen environment up to 14 kg/m3 oxygen and carbon dioxide regimes of the organism come to a new functional level which provides the adaptation to the extremal conditions. It is determined that an increase of physiological dead breathing space, a decrease of the rate of the O2 diffusion through the alveole-capillary barrier, intensification of unevenness of ventilator-perfusional relations in lungs and an increase of blood shunting in lungs are the main respiratory mechanisms which regulate mass transfer of O2 and CO2 in man under hyperbaria. The leading hemodynamic mechanism is the retention of volume blood circulation and cardiac output. It is studied how the compression rate, high partial pressures of oxygen and nitrogen, microclimate parameters in inhabited hypebaric chambers influence changes of functional breathing system. Absence of hypoxic state is proved in man (full saturation of man with nitrogen) under normoxia in nitrogen-oxygen environment with the density 6.34 kg/m3. These are also the data about accelerated rehabilitation of divers using the method of active adaptation o high altitudes. Basic directions in physiological studies of functional breathing system under increased pressure of gas and water environment are described.","PeriodicalId":40385,"journal":{"name":"Polish Hyperbaric Research","volume":"68 1","pages":"118 - 93"},"PeriodicalIF":0.2000,"publicationDate":"2019-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"3","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Polish Hyperbaric Research","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.2478/phr-2019-0014","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH","Score":null,"Total":0}
引用次数: 3

Abstract

Abstract There were evaluated responses of the respiratory system to changes in the variables of the external environment under increased pressure. To the model of professional underwater human activity underwater served the conditions of full saturation in compressed air or nitrogen-oxygen gas mixtures. Technical devices were presented by a number of underwater laboratories, mounted at the bottom (Ikhtiander-66, 67 and 68), hyperbaric chambers, submersible drilling rigs (Bur-1 and 2), and an autonomous diving Ikhtiander-2 for a long stay in the water. Studies of respiratory gases mass transport conditions in man showed than within the pressure range of 0.25-1.1 MPa at density of moderate hyperoxic and nitrogen-helio-oxygen environment up to 14 kg/m3 oxygen and carbon dioxide regimes of the organism come to a new functional level which provides the adaptation to the extremal conditions. It is determined that an increase of physiological dead breathing space, a decrease of the rate of the O2 diffusion through the alveole-capillary barrier, intensification of unevenness of ventilator-perfusional relations in lungs and an increase of blood shunting in lungs are the main respiratory mechanisms which regulate mass transfer of O2 and CO2 in man under hyperbaria. The leading hemodynamic mechanism is the retention of volume blood circulation and cardiac output. It is studied how the compression rate, high partial pressures of oxygen and nitrogen, microclimate parameters in inhabited hypebaric chambers influence changes of functional breathing system. Absence of hypoxic state is proved in man (full saturation of man with nitrogen) under normoxia in nitrogen-oxygen environment with the density 6.34 kg/m3. These are also the data about accelerated rehabilitation of divers using the method of active adaptation o high altitudes. Basic directions in physiological studies of functional breathing system under increased pressure of gas and water environment are described.
可居住的水下高压设备:在适应饱和氮氧高压时人体有机体的呼吸平衡
在压力增加的情况下,呼吸系统对外部环境变量变化的反应进行了评估。对于专业的水下人类活动模型,水下服务于压缩空气或氮气-氧气混合物的完全饱和条件。技术设备包括安装在底部的水下实验室(Ikhtiander-66、67和68)、高压舱、潜水钻机(Bur-1和2),以及可在水中长期停留的自主潜水Ikhtiander-2。对人体呼吸气体质量运输条件的研究表明,在0.25-1.1 MPa的压力范围内,在中等高氧和氮-氦-氧环境密度下,生物体的氧气和二氧化碳达到14 kg/m3,达到一个新的功能水平,提供了对极端条件的适应。结果表明:生理性死呼吸间隙增大、肺泡-毛细血管屏障O2扩散速率降低、肺内呼吸机-灌注关系不均匀性加剧、肺内血液分流增加是高压下人体调节O2和CO2传质的主要呼吸机制。主要的血流动力学机制是血循环容量和心输出量的保留。研究了有人居住的高压氧舱内的压缩率、高氧分压和高氧分压、小气候参数对功能呼吸系统变化的影响。在含氮-含氧环境下,人体无缺氧状态(含氮完全饱和),密度为6.34 kg/m3。这也是潜水员采用主动适应高海拔的方法加速康复的数据。介绍了气、水环境下功能性呼吸系统生理研究的基本方向。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
Polish Hyperbaric Research
Polish Hyperbaric Research PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH-
自引率
0.00%
发文量
6
审稿时长
9 weeks
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信
小红书