Experimental Studies of Geroprotective and Anti-Aging Effects of Chemical Compounds of Portulaca oleracea L. (Review)

IF 0.6 Q4 GERIATRICS & GERONTOLOGY
M. A. Berezutsky, N. A. Durnova, A. S. Sheremetyewa, U. A. Matvienko, M. N. Kurchatova
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引用次数: 0

Abstract

The analysis presented in the review of publications shows that extract of Portulaca oleracea L. or its individual components (polysaccharides, oleracea, alkaloids tetrahydroisoquinoline operatein E) is able to increase the lifespan of laboratory animals, to activate telomerase and increase telomere length, and to provide antioxidant and antiosteoclastogenic impact. Various neuroprotective effects (improvement of memory and learning ability, inhibition of acetylcholinesterase, protection of dopaminergic neurons, improvement of motor functions, etc.) are of interest for the prevention of syndromes associated with age-related degradation of the nervous system such as Alzheimer’s and Parkinson’s diseases. In addition, regular consumption of vegetable portulaca in food leads to a decrease in the percentage of cancer and cardiovascular diseases, which also directly provides an increase in the average life expectancy of the population.

马齿苋(马齿苋. L.)化学成分保护和抗衰老作用的实验研究(综述)
出版物综述中的分析表明,马齿苋提取物或其单个成分(多糖、马齿苋、生物碱四氢异喹啉操纵素E)能够延长实验动物的寿命,激活端粒酶并增加端粒长度,并提供抗氧化和抗破石作用。各种神经保护作用(改善记忆和学习能力、抑制乙酰胆碱酯酶、保护多巴胺能神经元、改善运动功能等)对预防与年龄相关的神经系统退化相关的综合征(如阿尔茨海默病和帕金森病)很有兴趣。此外,经常在食物中食用葡萄牙菜会降低癌症和心血管疾病的发病率,这也直接提高了人口的平均预期寿命。
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来源期刊
Advances in Gerontology
Advances in Gerontology GERIATRICS & GERONTOLOGY-
CiteScore
0.80
自引率
16.70%
发文量
45
期刊介绍: Advances in Gerontology focuses on biomedical aspects of aging. The journal also publishes original articles and reviews on progress in the following research areas: demography of aging; molecular and physiological mechanisms of aging, clinical gerontology and geriatrics, prevention of premature aging, medicosocial aspects of gerontology, and behavior and psychology of the elderly.
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