Melatonin Inhibitory Effects on Forming Brain Tumor

Abstract

Melatonin is a neurohormone secreted by the pineal and extra pineal organs with oncostatic and tumor inhibitory effects. There is considerable evidence that melatonin may be of use in the prevention and treatment of cancer. This manuscript will review some of the underlying molecular mechanisms by melatonin’s antitumor properties with emphasizing on the formation of brain tumors.