Finite Element Modeling of the Flexural Mechanical Response of Polymer-Coated Bioactive Glass Scaffolds Composed of Thermally-Bonded Unidirectional Fibers

Q1 Materials Science
W. Xiao, M. A. Zaeem, D. Day, M. Rahaman
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引用次数: 0

Abstract

Abstract Bioactive glasses have attractive characteristics as a scaffold material for healing bone defects but their brittle mechanical response, particularly in bending, is a concern. Recent studies have shown that coating the external surface of strong porous bioactive glass (13-93) scaffolds with an adherent biodegradable polymer layer can significantly improve their load-bearing capacity andwork of fracture, resulting in a non-brittle mechanical response. In the present study, finite element modeling (FEM) was used to analyze the mechanical response in four-point bending of composites composed of a porous glass scaffold and an adherent polymer surface layer. The glass scaffold with a cylindrical geometry (diameter = 4.2 mm; porosity = 20%) was composed of randomly arranged unidirectional fibers (diameter 200-700 μm) thatwere bonded at their contact points. The thickness of the polymer layer was 500 μm. By analyzing the stresses in the individual glass fibers, the simulations can account for the main trends in the observed mechanical response of practical composites with a similar architecture composed of a bioactive glass (13-93) scaffold and an adherent polylactic acid surface layer. These FEM simulations could play a useful role in designing bioactive glass composites with improved mechanical properties.
由热粘合单向纤维组成的聚合物涂层生物活性玻璃支架弯曲力学响应的有限元建模
摘要生物活性玻璃作为治疗骨缺损的支架材料具有吸引人的特性,但其脆性机械反应,特别是在弯曲时,令人担忧。最近的研究表明,在强多孔生物活性玻璃(13-93)支架的外表面涂覆一层粘附的可生物降解聚合物层,可以显著提高其承载能力和断裂功,从而产生非脆性的机械响应。在本研究中,使用有限元建模(FEM)来分析由多孔玻璃支架和粘附聚合物表面层组成的复合材料在四点弯曲中的力学响应。圆柱形几何结构(直径=4.2mm;孔隙率=20%)的玻璃支架由随机排列的单向纤维(直径200-700μm)组成,这些纤维在其接触点处结合。聚合物层的厚度为500μm。通过分析单个玻璃纤维中的应力,模拟可以解释具有由生物活性玻璃(13-93)支架和粘附的聚乳酸表面层组成的类似结构的实际复合材料的观察到的机械响应的主要趋势。这些有限元模拟可以在设计具有改进的机械性能的生物活性玻璃复合材料方面发挥有用的作用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Biomedical Glasses
Biomedical Glasses Materials Science-Surfaces, Coatings and Films
自引率
0.00%
发文量
0
审稿时长
17 weeks
期刊介绍: Biomedical Glasses is an international Open Access-only journal covering the field of glasses for biomedical applications. The scope of the journal covers the science and technology of glasses and glass-based materials intended for applications in medicine and dentistry. It includes: Chemistry, physics, structure, design and characterization of biomedical glasses Surface science and interactions of biomedical glasses with aqueous and biological media Modeling structure and reactivity of biomedical glasses and their interfaces Biocompatibility of biomedical glasses Processing of biomedical glasses to achieve specific forms and functionality Biomedical glass coatings and composites In vitro and in vivo evaluation of biomedical glasses Glasses and glass-ceramics in engineered regeneration of tissues and organs Glass-based devices for medical and dental applications Application of glasses and glass-ceramics in healthcare.
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