Optimization of antioxidant activity and bioactive compounds extraction of winter savory leaves by high hydrostatic pressure

IF 1.2 4区物理与天体物理 Q3 PHYSICS, MULTIDISCIPLINARY

High Pressure Research Pub Date : 2020-10-01 DOI:10.1080/08957959.2020.1830079

S. A. Moreira, M. Pintado, J. Saraiva

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引用次数: 5

Abstract

ABSTRACT Winter savory is often used in traditional medicine, having several recognized biological properties. This study aimed to evaluate the effect of high pressure-assisted extraction (HPE) and its optimization by response surface methodology to obtain winter savory extracts with a high content of bioactive compounds and high antioxidant activity (the effect of extraction pressure, extraction time, and ethanol concentration were investigated). Results showed that data could be well fitted to second-order polynomial mathematical models for total phenolics, total flavonoids, chlorophylls, carotenoids, and extraction yield, as well as for antioxidant activity. The models predicted optimal conditions ranging 200–500 MPa, extraction time 1–20 min, and ethanol concentration 0–70% (v,v). In comparison with extraction at atmospheric pressure, HPE showed to be more efficient, allowing obtaining an increase of about 40% for all compounds, and an increase of 29, 48, and 70% for antioxidant activity by FRAP, DPPH and ABTS assays, respectively. GRAPHICAL ABSTRACT

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高静压提取冬香叶抗氧化活性及生物活性成分的优化

摘要冬香通常用于传统医学，具有一些公认的生物学特性。本研究旨在评估高压辅助提取（HPE）的效果，并通过响应面法对其进行优化，以获得具有高含量生物活性化合物和高抗氧化活性的冬味提取物（研究了提取压力、提取时间和乙醇浓度的影响）。结果表明，数据可以很好地拟合总酚、总黄酮、叶绿素、类胡萝卜素、提取率以及抗氧化活性的二阶多项式数学模型。模型预测的最佳条件范围为200–500 MPa，萃取时间1–20 min，乙醇浓度为0–70%（v，v）。与大气压下的提取相比，HPE显示出更有效，通过FRAP、DPPH和ABTS测定，所有化合物的抗氧化活性分别提高了约40%，抗氧化活性分别增加了29%、48%和70%。图形摘要

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来源期刊

High Pressure Research 物理-物理：综合

CiteScore

3.80

自引率

5.00%

发文量

审稿时长

2 months

期刊介绍： High Pressure Research is the leading journal for research in high pressure science and technology. The journal publishes original full-length papers and short research reports of new developments, as well as timely review articles. It provides an important forum for the presentation of experimental and theoretical advances in high pressure science in subjects such as: condensed matter physics and chemistry geophysics and planetary physics synthesis of new materials chemical kinetics under high pressure industrial applications shockwaves in condensed matter instrumentation and techniques the application of pressure to food / biomaterials Theoretical papers of exceptionally high quality are also accepted.