Multiple myeloma of cranium with external ear canal swelling and occipital mass: A rare case report

IF 0.3 Q4 OTORHINOLARYNGOLOGY
Salla Kellberg, G. Kurdo, M. Kontro, S. Sinkkonen
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Abstract

Abstract Multiple myeloma (MM), the most common plasmacell neoplasm, manifests relatively often in the head and neck region, but rarely in the ear. We present a patient with fluctuating hearing loss, otalgia, persistent otitis externa and occipital swelling. CT imaging showed a large mass of cranium and the initial radiological diagnosis was plasmacytoma. Multiple osteolytic bone lesions, monoclonal serum protein with serum M component concentration of 35.2 g/L and bone marrow biopsy with abnormal, clonal plasma cells population confirmed the diagnosis of multiple myeloma. Although a rare manifestation in the external ear canal and its surroundings, plasmacytoma or multiple myeloma should be considered as a possible diagnosis in the presence of a scalp mass or a treatment resistant swelling of the external ear canal.
颅骨多发性骨髓瘤伴外耳道肿胀及枕部肿块1例报告
摘要多发性骨髓瘤(MM)是最常见的浆细胞肿瘤,相对常见于头颈部,但很少出现在耳朵。我们报告一位患者有波动性听力损失、耳痛、持续性外耳道炎和枕部肿胀。CT显示颅骨有大量肿块,初步放射学诊断为浆细胞瘤。多发性溶骨性病变,血清M组分浓度为35.2的单克隆血清蛋白 g/L和具有异常克隆性浆细胞群的骨髓活检证实了多发性骨髓瘤的诊断。尽管浆细胞瘤或多发性骨髓瘤在外耳道及其周围环境中是一种罕见的表现,但在存在头皮肿块或外耳道难治性肿胀的情况下,应将其视为一种可能的诊断。
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审稿时长
29 weeks
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