Larissa Fadin, Karolinny Cristiny de Oliveira Vieira, Ana Clara Campagnolo Gonçalves Toledo, A. K. D. da Silva, V. C. Pereira, L. Winkelstroter
{"title":"Probiotics in the Management of Antibiotic-Associated Diarrhea in Children","authors":"Larissa Fadin, Karolinny Cristiny de Oliveira Vieira, Ana Clara Campagnolo Gonçalves Toledo, A. K. D. da Silva, V. C. Pereira, L. Winkelstroter","doi":"10.1097/TIN.0000000000000332","DOIUrl":null,"url":null,"abstract":"This review aimed to evaluate probiotic use to prevent antibiotic-associated diarrhea in children. A total of 1564 studies of randomized clinical trials published in English were found using PubMed, Cochrane, and Virtual Health Library (MEDLINE/LILACS). A meta-analysis included 4 trials in subgroup Lactobacillus rhamnosus (95% confidence interval [CI]: 0.17-0.49; P < .00001), 2 trials in subgroup L reuteri (95% CI: 0.51-1.77; P = .87), and 5 groups in subgroup association of species of probiotics (95% CI: 0.21-1.71; P = .33). The findings suggest that L rhamnosus alone may be useful in preventing antibiotic-associated diarrhea in children.","PeriodicalId":0,"journal":{"name":"","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1097/TIN.0000000000000332","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
This review aimed to evaluate probiotic use to prevent antibiotic-associated diarrhea in children. A total of 1564 studies of randomized clinical trials published in English were found using PubMed, Cochrane, and Virtual Health Library (MEDLINE/LILACS). A meta-analysis included 4 trials in subgroup Lactobacillus rhamnosus (95% confidence interval [CI]: 0.17-0.49; P < .00001), 2 trials in subgroup L reuteri (95% CI: 0.51-1.77; P = .87), and 5 groups in subgroup association of species of probiotics (95% CI: 0.21-1.71; P = .33). The findings suggest that L rhamnosus alone may be useful in preventing antibiotic-associated diarrhea in children.