Probiotics in the Management of Antibiotic-Associated Diarrhea in Children

IF 0.4 4区医学 Q4 NUTRITION & DIETETICS

Topics in Clinical Nutrition Pub Date : 2023-07-01 DOI:10.1097/TIN.0000000000000332

Larissa Fadin, Karolinny Cristiny de Oliveira Vieira, Ana Clara Campagnolo Gonçalves Toledo, A. K. D. da Silva, V. C. Pereira, L. Winkelstroter

引用次数: 0

Abstract

This review aimed to evaluate probiotic use to prevent antibiotic-associated diarrhea in children. A total of 1564 studies of randomized clinical trials published in English were found using PubMed, Cochrane, and Virtual Health Library (MEDLINE/LILACS). A meta-analysis included 4 trials in subgroup Lactobacillus rhamnosus (95% confidence interval [CI]: 0.17-0.49; P < .00001), 2 trials in subgroup L reuteri (95% CI: 0.51-1.77; P = .87), and 5 groups in subgroup association of species of probiotics (95% CI: 0.21-1.71; P = .33). The findings suggest that L rhamnosus alone may be useful in preventing antibiotic-associated diarrhea in children.

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益生菌治疗儿童抗生素相关性腹泻

这篇综述旨在评估益生菌在预防儿童抗生素相关性腹泻中的应用。使用PubMed、Cochrane和虚拟健康图书馆（MEDLINE/LILACS）共发现了1564项以英语发表的随机临床试验研究。一项荟萃分析包括4项鼠李糖乳杆菌亚组试验（95%置信区间[CI]:0.17-0.49；P<.00001），2项路氏乳杆菌亚群试验（95%CI:0.51-1.77；P=.87），以及5组益生菌亚组关联试验（95%CI=0.21-1.71；P=.33）。研究结果表明，单独的鼠李糖可能有助于预防儿童抗生素相关性腹泻。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Topics in Clinical Nutrition NUTRITION & DIETETICS-

CiteScore

0.90

自引率

20.00%

发文量

期刊介绍： Topics in Clinical Nutrition (TICN) is a peer-reviewed, quarterly journal designed as a resource for the continuing education and clinical practice of dietitians and nutritionists. Each issue addresses topics of interest primarily to dietitians and nutritionists, students and interns in professional training programs and other health care personnel involved in the nutritional care of patients. Articles include translational research reports (work that applies new knowledge to practical effect), practice projects, evidence-based literature reviews, case studies and book reviews, and articles that highlight education theory and applied research which share the tools and techniques of nutrition and dietetics education.