Evaluation of Enhanced Adherence Counselling among Virally Unsuppressed HIV-Infected Adults on Antiretroviral Therapy in Suburban and Metropolitan parts of Delta State, Nigeria

Journal of community medicine & public health Pub Date : 2021-10-29 DOI:10.29011/2577-2228.100224

Lovina Nkechi Ukwueze, Casmir Ifeanyichukwu Cajetan Ifeanyi, Gladys, Adaku Iroegbu, Janet Aribike, N. F. Ikeneche

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引用次数: 1

Abstract

Background: Virally unsuppressed HIV-Infected persons are known to significantly increase the odds of HIV transmission. Though Enhanced Adherence Counselling (EAC) is recommended for improving viral loads outcomes, it is not a lone predictor for viral suppression. This study evaluated the impact of perceptions, psychosocial, economic and other characteristics of virally unsuppressed HIV-Infected adults on enhanced adherence counselling as a strategy for achieving viral suppression. Study design: A facility-based Cross-sectional study. Methods: This study evaluated 415 virally unsuppressed HIV-Infected adults after 6 months on antiretroviral therapy in comprehensive health facilities in Delta State. Structured questionnaire were administered on randomly sampled HIV-Infected adults at the hospitals on their clinic appointments. Data captured into Epi Info 7.0 were analyzed with SPSS 20.0. Chi square was used to determine relationships considering P< 0.05 statistically significant. Results: Of the 415 virally unsuppressed HIV-infected adults evaluated, 49.1% admitted tiresomeness in taking ARVs; 31.5% of subjects reported on the inefficacy of the ARV drugs, while 19.4% of the subjects said that they had issues with the ARV pills burden. Non-adherence to ARV drugs regimen were observed in 74.1% of the HIV-infected adults studied. More than half (50.9%) of the subjects missed their ARV drugs regimen in the past 3 months. Equally, 28.7% and 17.6% of HIV-infected adults had missed their ARV drugs regimen within 1-5 months and for more than 5 months respectively. Conclusions: This study reveals the association of virally unsuppressed HIV infections with non-adherence to ARV regimen due to forgetfulness, faith-healing belief and taking of herbal medicine. Citation: Ukwueze LN, Ifeanyi CIC, Iroegbu GA, Aribike J, Ikeneche NF (2021) Evaluation of Enhanced Adherence Counselling among Virally Unsuppressed HIV-Infected Adults on Antiretroviral Therapy in Suburban and Metropolitan parts of Delta State, Nigeria. J Community Med Public Health 5: 224. DOI: 10.29011/2577-2228.100224 2 Volume 5; Issue 04 J Community Med Public Health, an open access journal ISSN: 2577-2228

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对尼日利亚三角洲州郊区和大都市地区病毒未受抑制的艾滋病毒感染成人抗逆转录病毒治疗依从性加强咨询的评价

背景:已知病毒未抑制的HIV感染者显著增加了HIV传播的几率。虽然强化依从性咨询(EAC)被推荐用于改善病毒载量结果，但它并不是病毒抑制的唯一预测因子。本研究评估了未受病毒抑制的艾滋病毒感染成人的观念、社会心理、经济和其他特征对加强依从性咨询作为实现病毒抑制的策略的影响。研究设计:以设施为基础的横断面研究。方法:本研究评估了415名在三角洲州综合卫生机构接受抗逆转录病毒治疗6个月后病毒未受抑制的艾滋病毒感染成人。在医院门诊预约时，对随机抽样的艾滋病毒感染成人进行结构化问卷调查。Epi Info 7.0采集的数据用SPSS 20.0进行分析。采用卡方检验，认为P< 0.05有统计学意义。结果:在接受评估的415名病毒未受抑制的hiv感染成人中，49.1%承认服用抗逆转录病毒药物感到厌烦;31.5%的受试者报告抗逆转录病毒药物无效，而19.4%的受试者表示他们对抗逆转录病毒药物负担有问题。74.1%的hiv感染成人不遵守抗逆转录病毒药物治疗方案。超过一半(50.9%)的受试者在过去3个月内未接受抗逆转录病毒药物治疗。同样，28.7%和17.6%感染艾滋病毒的成年人分别在1-5个月内和超过5个月没有服用抗逆转录病毒药物。结论:本研究揭示了病毒未抑制的HIV感染与由于健忘、信仰治疗信念和服用草药而不遵守抗逆转录病毒治疗方案的关联。引用本文:Ukwueze LN, Ifeanyi CIC, Iroegbu GA, Aribike J, Ikeneche NF(2021)对尼日利亚三角洲州郊区和大都市地区病毒未抑制的hiv感染成人抗逆转录病毒治疗的强化依从性咨询评估。[J]社区医学与公共卫生，5:24 - 24。DOI: 10.29011/2577-2228.100224 2卷5;第04期J Community Med Public Health，开放获取期刊ISSN: 2577-2228

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Journal of community medicine & public health

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