A comparative analysis of ambulatory blood pressure characteristics in acute stroke and non-stroke Indian patients.

IF 16.4 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Accounts of Chemical Research Pub Date : 2023-12-01 Epub Date: 2023-08-02 DOI:10.1097/MBP.0000000000000664

Subhaschandra B Hegde, Shivaramakrishna Aroor, Yedabettu Janardana Anupama, Shrikanth N Hegde, Hiren Prajapati, Willem J Verberk

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引用次数: 0

Abstract

Objective: The objective of this study is to identify 24-h blood pressure (BP) characteristics after acute stroke in Indian hospitalized patients.

Methods: In total, 769 patients [284 women (36.9%)] admitted at a hospital in South India were analyzed. Of these, 364 patients (47.3%) had recently experienced stroke. All patients underwent ambulatory blood pressure measurement (ABPM) so that ABPM patterns and ABPM risk parameters of stroke and non-stroke patients could be compared. Additionally, to investigate the relationship between ABPM parameters and stroke, a stepwise logistic regression analysis was employed.

Results: Stroke patients had significantly higher BP than non-stroke patients (24-h ABP: 145.0 ± 22.1 vs. 133.7 ± 20.5 mmHg, P < 0.001), with similar dipping status. ABPM parameters mostly associated with stroke (all P < 0.001) were: nighttime [odds ratios (OR): 1.587, 95% confidence interval (95% CI): 1.341-1.885], 24-h (1.584, 1.34-1.881), minimum nighttime (1.582, 1.339-1.879), daytime (1.540, 1.304-1.827), and morning SBP (1.517, 1.287-1.797). Non-dipping status was relatively more common in stroke patients (79% vs. 71%, P < 0.05) but dipping percentage did not show a significant linear relationship with stroke.

Conclusion: Several ABPM characteristics were strongly associated with stroke in Indian hospitalized patients. Specifically, minimum nighttime and average morning SBP may be considered as important and practical parameters for its relationship with stroke.

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印度急性脑卒中和非脑卒中患者动态血压特征的比较分析

本研究的目的是确定印度住院患者急性卒中后24小时血压（BP）的特征。总共对南印度一家医院收治的769名患者【284名女性（36.9%）】进行了分析。其中，364名患者（47.3%）最近经历过中风。所有患者都接受了动态血压测量（ABPM），以便比较中风和非中风患者的ABPM模式和ABPM风险参数。此外，为了研究ABPM参数与中风之间的关系，采用了逐步逻辑回归分析。脑卒中患者的血压明显高于非脑卒中患者（24小时ABP:145.0 ± 22.1对133.7 ± 20.5 mmHg，P < 0.001），具有相似的倾斜状态。ABPM参数主要与中风相关（所有P < 0.001）分别为：夜间[比值比（OR）:1.587，95%置信区间（95%CI）:1.341-1.885]，24小时（1.584，1.34-1.881），夜间最小值（1.582，1.339-1.879），白天（1.540，1.304-1.827）和早晨收缩压（1.517，1.287-1.797） < 0.05），但下降百分比与中风没有显著的线性关系。印度住院患者的几个ABPM特征与中风密切相关。具体而言，夜间最小收缩压和早晨平均收缩压可被认为是其与中风关系的重要和实用的参数。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Accounts of Chemical Research 化学-化学综合

CiteScore

31.40

自引率

1.10%

发文量

312

审稿时长

2 months

期刊介绍： Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.