Novel biomarker and drug delivery systems for theranostics – extracellular vesicles

IF 1.2 Q3 Computer Science

Bio-Algorithms and Med-Systems Pub Date : 2021-12-01 DOI:10.1515/bams-2021-0183

E. Stępień, Carina Rząca, P. Moskal

引用次数: 9

Abstract

Abstract Extracellular vesicles (EVs) are nano- and micro-sized double-layered membrane entities derived from most cell types and released into biological fluids. Biological properties (cell-uptake, biocompatibility), and chemical (composition, structure) or physical (size, density) characteristics make EVs a good candidate for drug delivery systems (DDS). Recent advances in the field of EVs (e.g., scaling-up production, purification) and developments of new imaging methods (total-body positron emission tomography [PET]) revealed benefits of radiolabeled EVs in diagnostic and interventional medicine as a potential DDs in theranostics.

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用于治疗的新型生物标志物和药物传递系统——细胞外囊泡

细胞外囊泡(EVs)是一种纳米级和微级的双层膜实体，来源于大多数细胞类型，并释放到生物流体中。生物特性(细胞摄取、生物相容性)、化学特性(组成、结构)或物理特性(大小、密度)使ev成为药物递送系统(DDS)的良好候选者。随着电动汽车领域的最新进展(如规模化生产、纯化)和新成像方法(全身正电子发射断层扫描[PET])的发展，放射性标记电动汽车在诊断和介入医学中作为治疗学中潜在的ddds有很大的价值。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Bio-Algorithms and Med-Systems MATHEMATICAL & COMPUTATIONAL BIOLOGY-

CiteScore

3.80

自引率

0.00%

发文量

期刊介绍： The journal Bio-Algorithms and Med-Systems (BAMS), edited by the Jagiellonian University Medical College, provides a forum for the exchange of information in the interdisciplinary fields of computational methods applied in medicine, presenting new algorithms and databases that allows the progress in collaborations between medicine, informatics, physics, and biochemistry. Projects linking specialists representing these disciplines are welcome to be published in this Journal. Articles in BAMS are published in English. Topics Bioinformatics Systems biology Telemedicine E-Learning in Medicine Patient''s electronic record Image processing Medical databases.