Risk Factors of Worsening of Systemic Lupus Erythematosus in Patients at Two Tertiary Hospitals in Jakarta

IF 0.4 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH
Giri Aji, M. K. Sudaryo, Ratna Djuwita, S. Sukamto
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引用次数: 0

Abstract

Systemic Lupus Erythematosus (SLE) is a prototypical multiorgan autoimmune disease with a fluctuating and chronic disease course. As an emerging disease in this century, SLE will burden stakeholders and the country. This study was conducted to determine the prognostic factors for SLE worsening, especially in ambulatory patients. This ambispective study used logistic regression to view the risk factors for worsening SLE in patients. Anemia, age, body mass index, education level, employment status, marital status, hydroxychloroquine, and immunosuppressants were the independent variables in this study. This study concludes that anemia is statistically significant and, therefore, a risk factor for worsening SLE in patients (RR = 5.31; p-value<0.005), while age, body mass index, education level, employment status, marital status, hydroxychloroquine, and immunosuppressants are not statistically significant.
雅加达两家三级医院患者系统性红斑狼疮恶化的危险因素
系统性红斑狼疮(SLE)是一种典型的多器官自身免疫性疾病,具有波动和慢性病程。SLE作为本世纪新出现的疾病,将给利益相关者和国家带来负担。本研究旨在确定SLE恶化的预后因素,特别是在流动患者中。本研究采用logistic回归分析观察SLE患者恶化的危险因素。贫血、年龄、体重指数、受教育程度、就业状况、婚姻状况、羟氯喹、免疫抑制剂是本研究的自变量。本研究的结论是,贫血具有统计学意义,是SLE患者恶化的危险因素(RR = 5.31;p值<0.005),而年龄、体重指数、受教育程度、就业状况、婚姻状况、羟氯喹、免疫抑制剂的差异无统计学意义。
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来源期刊
Kesmas-National Public Health Journal
Kesmas-National Public Health Journal PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH-
CiteScore
1.70
自引率
0.00%
发文量
39
审稿时长
10 weeks
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