Novel Imaging Technologies for Accurate Assessment of Cardiac Allograft Performance.

IF 2.4 Q2 SURGERY

Current Transplantation Reports Pub Date : 2023-09-01 Epub Date: 2023-07-17 DOI:10.1007/s40472-023-00400-w

Manuela Lopera Higuita, Rohil Jain, Asishana A Osho, S Alireza Rabi, Timothy L Pruett, Richard N Pierson, Paul A Iaizzo, Shannon N Tessier

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引用次数: 0

Abstract

Purpose of the review: The current lack of objective and quantitative assessment techniques to determine cardiac graft relative viability results in risk-averse decision-making, which negatively impact the utilization of cardiac grafts. The purpose of this review is to highlight the current deficiencies in cardiac allograft assessment before focusing on novel cardiac assessment techniques that exploit conventional and emerging imaging modalities, including ultrasound, magnetic resonance, and spectroscopy.

Recent findings: Extensive work is ongoing by the scientific community to identify improved objective metrics and tools for cardiac graft assessment, with the goal to safely increasing the number and proportion of hearts accepted for transplantation.

Summary: This review briefly discusses the in situ and ex vivo tools currently available for clinical organ assessment, before focusing on the individual capabilities of ultrasound, magnetic resonance, and spectroscopy to provide insightful, non-invasive information regarding cardiac graft functional and metabolic status that may be used to predict outcome after transplantation.

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用于精确评估心脏移植物性能的新型成像技术

综述的目的：目前缺乏客观、定量的评估技术来确定心脏移植物的相对存活率，这导致了规避风险的决策，对心脏移植物的利用产生了负面影响。本综述旨在强调目前在心脏同种异体移植评估方面存在的不足，然后重点介绍利用传统和新兴成像模式（包括超声、磁共振和光谱学）的新型心脏评估技术：摘要：本综述简要讨论了目前可用于临床器官评估的原位和体外工具，然后重点介绍了超声波、磁共振和光谱学在提供有关心脏移植物功能和代谢状态的深入、非侵入性信息方面的各自能力，这些信息可用于预测移植后的预后。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Current Transplantation Reports Medicine-Surgery

CiteScore

3.40

自引率

4.80%

发文量

期刊介绍： Under the guidance of Dr. Dorry Segev, from Johns Hopkins, Current Transplantation Reports will provide an in-depth review of topics covering kidney, liver, and pancreatic transplantation in addition to immunology and composite allografts.We accomplish this aim by inviting international authorities to contribute review articles that emphasize new developments and recently published papers of major importance, highlighted by annotated reference lists. By providing clear, insightful balanced contributions, the journal intends to serve those involved in the field of transplantation.