Fetus is Mature after 32 Weeks of Pregnancy

Abstract

Aim: Fetal maturity was estimated by various methods in 164 monochorionic diamniotic (MD) twins. Methods: Twin-to-tin transfusion syndrome (TTTS) was prevented by intensive maternal rest and tocolysis until Fetal adrenal cortex maturity, which was estimated in the initiation mechanism of uterine contraction, gray level histogram width (GLHW) of fetal lung and liver ratio multiplied by gestational weeks was used to estimate fetal lung maturity. Results and discussion: Fetal adreno-cortical steroid, reacted stresses after maturation, which caused Braxton- Hicks uterine contraction after 30 gestational weeks, where ultrasonic cardio-thprax ratio enlarged to 0.4 or more, then the MD twins received Caesarean delivery to prevent TTTS in 32 ± 2.2 gestational weeks where coefficient of variation (CV) of weeks was as small as 7%. Thus, fetal maturity was estimated to be 32 gestational weeks. As GLHW ratio of fetal lung and liver multiplied by gestational weeks was >29 in mature fetal lung, the index was 31 in 32 gestational weeks, and no problem was found in the iMD twins born in 32 ± 2.2 gestational weeks. Conclusion: Human fetus is mature in 32 gestational weeks.