Biological Synthesis of Silver Nanoparticles and their Biomedical Activity: A Review

IF 1.1 Q3 CHEMISTRY, MULTIDISCIPLINARY
S. Zafar, Aiman Zafar, F. Jabeen, M. Siddiq
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引用次数: 0

Abstract

Nanotechnology studies the various phenomena of physio-chemical procedures and biological properties for the generation of nanosized particles, and their rising challenges in the various sectors, like medicine, engineering, agriculture, electronic, and environmental studies. The nanosized particles exhibit good anti-microbial, anti-inflammatory, cytotoxic, drug delivery, anti-parasitic, anti-coagulant and catalytic properties because of their unique dimensions with large surface area, chemical stability and higher binding density for the accumulation of various bio-constituents on their surfaces. Biological approaches for the synthesis of silver nanoparticles (AgNPs) have been reviewed because it is an easy and single-step protocol and a viable substitute for the synthetic chemical-based procedures. Physical and chemical approaches for the production of AgNPs are also mentioned herein. Biological synthesis has drawn attention because it is cost-effective, faster, non-pathogenic, environment-friendly, easy to scale-up for large-scale synthesis, and having no demand for usage of high pressure, energy, temperature, or noxious chemical ingredients, and safe for human therapeutic use. Therefore, the collaboration of nanomaterials with bio-green approaches could extend the utilization of biological and cytological properties compatible with AgNPs. In this perspective, there is an immediate need to develop ecofriendly and biocompatible techniques, which strengthen efficacy against microbes and minimize toxicity for human cells. The present study introduces the biological synthesis of silver nanoparticles, and their potential biomedical applications have also been reviewed.
纳米银的生物合成及其生物医学活性研究进展
纳米技术研究产生纳米粒子的各种物理化学过程和生物特性的现象,以及它们在医学、工程、农业、电子和环境研究等各个领域面临的日益增长的挑战。纳米级颗粒具有良好的抗微生物、抗炎、细胞毒性、药物传递、抗寄生虫、抗凝血和催化性能,因为它们具有独特的尺寸,具有大的表面积、化学稳定性和更高的结合密度,可以在其表面积累各种生物成分。生物合成银纳米颗粒(AgNPs)的方法已经被回顾,因为它是一种简单的单步方案,是合成化学基础程序的可行替代品。本文还提到了生产AgNPs的物理和化学方法。生物合成因其具有成本效益高、速度快、无致病性、环境友好、易于大规模合成、不需要使用高压、能量、温度和有毒化学成分、对人体治疗安全等优点而备受关注。因此,纳米材料与生物绿色方法的合作可以扩展与AgNPs兼容的生物学和细胞学特性的利用。从这个角度来看,迫切需要开发生态友好和生物相容性的技术,以加强对微生物的功效并最大限度地减少对人体细胞的毒性。本文介绍了纳米银的生物合成方法,并对其潜在的生物医学应用进行了综述。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Current Green Chemistry
Current Green Chemistry CHEMISTRY, MULTIDISCIPLINARY-
CiteScore
4.30
自引率
13.60%
发文量
6
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