The foraging Gene and Its Behavioral Effects: Pleiotropy and Plasticity.

IF 8.7 1区生物学 Q1 GENETICS & HEREDITY

Annual review of genetics Pub Date : 2019-12-03 DOI:10.1146/annurev-genet-112618-043536

I. Anreiter, M. Sokolowski

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引用次数: 45

Abstract

The Drosophila melanogaster foraging ( for) gene is a well-established example of a gene with major effects on behavior and natural variation. This gene is best known for underlying the behavioral strategies of rover and sitter foraging larvae, having been mapped and named for this phenotype. Nevertheless, in the last three decades an extensive array of studies describing for's role as a modifier of behavior in a wide range of phenotypes, in both Drosophila and other organisms, has emerged. Furthermore, recent work reveals new insights into the genetic and molecular underpinnings of how for affects these phenotypes. In this article, we discuss the history of the for gene and its role in natural variation in behavior, plasticity, and behavioral pleiotropy, with special attention to recent findings on the molecular structure and transcriptional regulation of this gene. Expected final online publication date for the Annual Review of Genetics, Volume 53 is November 23, 2019. Please see http://www.annualreviews.org/page/journal/pubdates for revised estimates.

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觅食基因及其行为效应：立体性和可塑性。

果蝇觅食(for)基因是对行为和自然变异有重大影响的基因的一个公认的例子。这一基因最为人所知的是，它是流浪者和保姆觅食幼虫的行为策略的基础，已被绘制并命名为这种表型。尽管如此，在过去的三十年中，大量的研究描述了在果蝇和其他生物体中，作为一种广泛的表现型的行为调节剂的作用。此外，最近的工作揭示了对如何影响这些表型的遗传和分子基础的新见解。在这篇文章中，我们讨论了for基因的历史及其在行为、可塑性和行为多效性的自然变异中的作用，并特别关注了该基因的分子结构和转录调控的最新发现。《遗传学年度评论》第53卷的最终在线出版日期预计为2019年11月23日。修订后的估计数请参阅http://www.annualreviews.org/page/journal/pubdates。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Annual review of genetics 生物-遗传学

CiteScore

18.30

自引率

0.90%

发文量

期刊介绍： The Annual Review of Genetics, published since 1967, comprehensively covers significant advancements in genetics. It encompasses various areas such as biochemical, behavioral, cell, and developmental genetics, evolutionary and population genetics, chromosome structure and transmission, gene function and expression, mutation and repair, genomics, immunogenetics, and other topics related to the genetics of viruses, bacteria, fungi, plants, animals, and humans.