{"title":"Hypoglycemic potential of Elaeagnus angustifolia fruit polysaccharide on streptozotocin-induced type 2 diabetic mice","authors":"Ya Wang, H. Zou, Cui Sun, Tao Guo, Zaiping Feng","doi":"10.3329/BJP.V13I4.37069","DOIUrl":null,"url":null,"abstract":"<p class=\"Abstract\">In this study, the hyperglycemic potential of Elaeagnus angustifolia fruit polysaccharide in both normal healthy and streptozotocin-induced diabetic mice was investigated. Results showed no significant effect of E. angustifolia fruit polysaccharide on blood glucose level in normal control group, while E. angustifolia significantly suppressed the rise in blood glucose of diabetic mice. In addition, in the first two weeks of administration, the body weight was decreased both in negative control group and E. angustifolia groups, however, E. angustifolia (800 mg/kg) was recovered to the began weight in the fourth week. E. angustifolia (800 mg/kg) could markedly reduce the levels of total cholesterol, triglyceride and improve the level of high density lipoprotein-cholesterol. The results suggest that E. angustifolia could be considered as an ingredient of functional foods for diabetes.</p><p><strong>Video Clip of Methodology:</strong></p><p>10 min 19 sec <a href=\"https://www.youtube.com/v/a3ikXeeByP8\">Full Screen</a> <a href=\"https://www.youtube.com/watch?v=a3ikXeeByP8\">Alternate</a> </p>","PeriodicalId":8719,"journal":{"name":"Bangladesh Journal of Pharmacology","volume":null,"pages":null},"PeriodicalIF":0.9000,"publicationDate":"2018-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3329/BJP.V13I4.37069","citationCount":"6","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Bangladesh Journal of Pharmacology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.3329/BJP.V13I4.37069","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"PHARMACOLOGY & PHARMACY","Score":null,"Total":0}
引用次数: 6
Abstract
In this study, the hyperglycemic potential of Elaeagnus angustifolia fruit polysaccharide in both normal healthy and streptozotocin-induced diabetic mice was investigated. Results showed no significant effect of E. angustifolia fruit polysaccharide on blood glucose level in normal control group, while E. angustifolia significantly suppressed the rise in blood glucose of diabetic mice. In addition, in the first two weeks of administration, the body weight was decreased both in negative control group and E. angustifolia groups, however, E. angustifolia (800 mg/kg) was recovered to the began weight in the fourth week. E. angustifolia (800 mg/kg) could markedly reduce the levels of total cholesterol, triglyceride and improve the level of high density lipoprotein-cholesterol. The results suggest that E. angustifolia could be considered as an ingredient of functional foods for diabetes.
期刊介绍：
Bangladesh Journal of Pharmacology (Bangladesh J Pharmacol) is an open access, video component, peer-reviewed journal of the Bangladesh Pharmacological Society (BDPS).
A scholarly publication is defined ''open access'' when there are no financial, legal or technical barriers to accessing it. Anyone can read, download, copy, distribute, print or use it in educational purpose within the legal agreements.
Peer review of a manuscript means the evaluation of research work by one or more people with similar competences. It can be open or blind. We do the single-blind peer review.
Our readers want to know the methodology used by the researchers which is very important to get the results. The video clip of one of the methodologies is prepared by the authors and submit it to publish.
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