Mycobiome and Microbiome in Seborrheic Dermatitis

Q4 Medicine

Journal of Mycology and Infection Pub Date : 2022-03-31 DOI:10.17966/jmi.2022.27.1.9

Dong Heon Lee, H. Jung

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Abstract

Seborrheic dermatitis (SD) is a chronic inflammatory skin disease in which scaling and erythema occur on various body parts, such as the scalp, eyebrows, nasolabial folds, and ears. Although it is a common skin disease, its pathogenesis remains unclear. It has various causes, including microorganisms and immune and nervous system abnormalities that act in a complex manner. The skin mycobiome/microbiome, an important factor in SD occurrence, is being actively studied. Among the skin microorganisms related to SD, Malassezia and Cutibacterium have been extensively studied. Recently, it was revealed that various microorganisms are related in several ways. The study of changes in mycobiome/microbiome involves comparing types and abundances of microorganisms and degrees of microbial diversity; patients and healthy individuals; the lesion and nonlesion areas; and affected body parts. Several studies on the mycobiome/microbiome associated with SD have shown relatively consistent results; however, some have revealed different outcomes. These variations occur because of differences in individuals, study groups, and sampling/study methodology. Therefore, further research is needed for the application the results of these studies in the treatment of SD.

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脂溢性皮炎的真菌和微生物组

脂溢性皮炎（SD）是一种慢性炎症性皮肤病，在头皮、眉毛、鼻唇沟和耳朵等身体各个部位都会出现鳞屑和红斑。尽管它是一种常见的皮肤病，但其发病机制尚不清楚。它有多种原因，包括微生物以及以复杂方式发挥作用的免疫和神经系统功能。皮肤真菌生物群落/微生物组是SD发生的一个重要因素，目前正在积极研究中。在与SD相关的皮肤微生物中，马拉色菌和Cutibacterium已被广泛研究。最近，人们发现各种微生物在几个方面有联系。真菌生物群落/微生物组变化的研究包括比较微生物的类型和丰度以及微生物多样性的程度；患者和健康个体；病变和非病变区域；以及受影响的身体部位。关于与SD相关的真菌生物群落/微生物组的几项研究显示了相对一致的结果；然而，一些人揭示了不同的结果。这些变化的发生是由于个体、研究组和抽样/研究方法的差异。因此，需要进一步研究这些研究结果在SD治疗中的应用。

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来源期刊

Journal of Mycology and Infection Medicine-Infectious Diseases

CiteScore

0.20

自引率

0.00%

发文量

期刊介绍： The Journal of mycology and infection (Acronym: JMI, Abbreviation: J Mycol Infect) aims to publish articles of exceptional interests in the field of medical mycology. The journal originally was launched in 1996 as the Korean Journal of Medical Mycology and has reformed into the current state beginning on March of 2018. The contents of the journal should elucidate important microbiological fundamentals and provide qualitative insights to respective clinical aspects. JMI underlines the submission of novel findings and studies in clinical mycology that are enriched by analyses achieved through investigative methods. The journal should be of general interests to the scientific communities at large and should provide medical societies with advanced breadth and depth of mycological expertise. In addition, the journal supplements infectious diseases in adjunct to the field of mycology to address a well-rounded understanding of infectious disorders. The Journal of mycology and infection, which is issued quarterly, in March, June, September and December each year, published in English. The scope of the Journal of mycology and infection includes invited reviews, original articles, case reports, letter to the editor, and images in mycology. The journal is compliant to peer-review/open access and all articles undergo rigorous reviewing processes by our internationally acknowledged team of editorial boards. The articles directed to publication should encompass in-depth materials that employ scholastic values of mycology and various infectious diseases. Articles responding to critical methodology and outcomes which have potential to enhance better understanding of mycology and infectious diseases are also suitable for publication.