Influence of Non-Hormonal Intervention On Lipid Profile Among Perimenopausal Women.

Abstract

This study aims to find the effect of a non-hormonal therapy to help solve dyslipidemia among perimenopausalwomen. The objective of achieving this aim was to find the effect of soya supplementation on low-density lipoprotein (LDL),high-density lipoprotein (HDL), and total cholesterol (TCL) levels among perimenopausal women with dyslipidemia. This singleblindedquasi-experimental study was conducted in a rural community in southern India with 54 perimenopausal women in 40-55 age. The subjects were randomized into a control group that received only structured health education and an experimentalgroup that received structured health education, and soya supplements 50 grams of soya meal curry on alternative days for 3days a week for 16 weeks. The three-outcome analysis for the study HDL, LDL, and TCL levels was analyzed as a part ofbaseline selection criteria (Pre-test), following 8 weeks (Post-test 1) and 16th weeks (Post-test 2), respectively. The study resultsshowed that all three biomarkers normalized significantly better in the experimental group than in the control group. The studysupports the statement that a soya diet can be an adjunct to estrogen therapy. Hence, the study favors using a soya diet as atreatment choice for managing dyslipidemia among perimenopausal women.