The Study of Suicidal Behavior and Indicators of Electrolyte Blood Composition in Borderline Mental Disorders under the Influence of Combined Psychopharmacotherapy

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Abstract

The formation of new approaches to the treatment of neurotic disorders, taking into account pathogenetic mechanisms, is an urgent task in neurology and psychiatry, due to the high prevalence of this group of diseases, the risk of developing suicidal behavior, a negative impact on the quality of human life, aggravating the course of somatic diseases, contributing to the development of physical and mental and social maladaptation with limited professional activity and disability. According to the WHO, in 2015 Anxiety Depressive Disorder (MAD) caused 50 million people to be disabled. A disappointing forecast of WHO experts is that while maintaining current trends in the spread of the disease by 2020, TDR will be in second place after coronary heart disease in the number of years lost due to disability [6]. In this regard, the purpose of this study was to study the structure of depressive disorders, suicidal behavior of patients in the Republic of Mordovia (Russia), as well as to study the characteristics of the course of psychopathological anxiety-depressive disorders in the framework of the most frequent nosological forms of diseases in Mordovia - neurotic and reactive depressions, as well as chronic forms - neurotic personality development in comparison with psychopathy under the influence of traditional psychopharmacotherapy and combined treatment with antioxidant drugs.
精神药物联合治疗对边缘性精神障碍患者自杀行为及电解质血液成分指标的影响
考虑到发病机制,形成治疗神经性疾病的新方法是神经病学和精神病学的一项紧迫任务,因为这类疾病的高患病率、发展自杀行为的风险、对人类生活质量的负面影响、加重躯体疾病的进程,导致身体、心理和社会适应不良,职业活动有限,残疾。根据世界卫生组织的数据,2015年,焦虑抑郁障碍(MAD)导致5000万人残疾。世界卫生组织专家的一个令人失望的预测是,尽管到2020年保持了疾病传播的当前趋势,但TDR在因残疾而丧失的年数方面将排在冠心病之后[6]。在这方面,本研究的目的是研究摩尔多瓦共和国(俄罗斯)患者的抑郁障碍结构和自杀行为,并在摩尔多瓦最常见的疾病类型——神经性和反应性抑郁——的框架下研究精神病理学焦虑抑郁障碍的病程特征,以及慢性形式——在传统心理药物治疗和抗氧化药物联合治疗的影响下,与精神病相比,神经性人格的发展。
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