Antibacterial wound dressing with hydrogel from chitosan and polyvinyl alcohol from the red cabbage extract loaded with silver nanoparticles

IF 3.8 4区工程技术 Q2 CHEMISTRY, MULTIDISCIPLINARY

Green Processing and Synthesis Pub Date : 2023-01-01 DOI:10.1515/gps-2023-0035

Kumaravel Kaliaperumal, K. Subramanian, R. Thirunavukkarasu, Ramesh Kumar Varadharajan, Reem Binsuwaidan, N. Alabdallah, N. Alshammari, Mohd Saeed, K. Anbarasu, R. Karunakaran

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引用次数: 1

Abstract

Abstract The aim of the present study was the synthesis of hydrogel incorporated with chitosan blend with polyvinyl alcohol (PVA) from red cabbage Brassica oleracea and its application in wound healing and antibacterial activity. The chitosan/PVA hydrogel was synthesized by the combination of chitosan and PVA treated with acetic acid. The silver nanoparticles (AgNPs) were synthesized from the B. oleracea extract and its antibacterial efficacy was examined. The synthesized nanoparticles (NPs) were characterized using UV-spectroscopy and X-ray diffraction methods. The synthesized NPs were purified and combined with the hydrogel. This combined hydrogel and AgNP mixture was then subjected to Fourier transform infrared analysis, and the results were observed to conclude the effectiveness of the hydrogel. This hydrogel would differ in the part of dressing the wound, that is it can last on the wound for a longer period, thus reducing the pain and frequency of dressing and in turn naturally healing the wound in less time.

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壳聚糖水凝胶和负载银纳米粒子的红甘蓝提取物聚乙烯醇抗菌伤口敷料

摘要研究了壳聚糖与聚乙烯醇(PVA)共混水凝胶的合成及其在甘蓝伤口愈合和抗菌方面的应用。以壳聚糖和聚乙烯醇为原料，经乙酸处理，合成了壳聚糖/聚乙烯醇水凝胶。以甘蓝提取物为原料合成银纳米颗粒(AgNPs)，并对其抑菌效果进行了研究。利用紫外光谱法和x射线衍射法对合成的纳米颗粒进行了表征。对合成的NPs进行纯化并与水凝胶结合。然后对这种水凝胶和AgNP混合物进行傅里叶变换红外分析，并观察结果，得出水凝胶的有效性。这种水凝胶的不同之处在于，它可以在伤口上停留更长的时间，从而减少伤口的疼痛和频率，从而在更短的时间内自然愈合伤口。

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来源期刊

Green Processing and Synthesis CHEMISTRY, MULTIDISCIPLINARY-ENGINEERING, CHEMICAL

CiteScore

6.70

自引率

9.30%

发文量

审稿时长

7 weeks

期刊介绍： Green Processing and Synthesis is a bimonthly, peer-reviewed journal that provides up-to-date research both on fundamental as well as applied aspects of innovative green process development and chemical synthesis, giving an appropriate share to industrial views. The contributions are cutting edge, high-impact, authoritative, and provide both pros and cons of potential technologies. Green Processing and Synthesis provides a platform for scientists and engineers, especially chemists and chemical engineers, but is also open for interdisciplinary research from other areas such as physics, materials science, or catalysis.