T. Vilches, G. B. de Almeida, C.M.C.B. Fortaleza, C. Ferreira
{"title":"IMPROVING CONTROL STRATEGIES OF INFECTIONS BY RESISTANT PATHOGENS IN A HOSPITAL NETWORK","authors":"T. Vilches, G. B. de Almeida, C.M.C.B. Fortaleza, C. Ferreira","doi":"10.1142/s0218339023500262","DOIUrl":null,"url":null,"abstract":"The efficacy of infection prevention and control on several hospital networks is assessed. We tested two kinds of strategy, a network-topology-based allocation and a [Formula: see text]-based allocation, where [Formula: see text] is the basic reproduction number of the infection. For this, a multi-patch deterministic model simulates the spread of carbapenemase-producing Enterobacteriaceae in several theoretical hospital networks parametrized by data from Brazil. Our results show that: (i) the allocation methods based on the [Formula: see text] of the hospitals may work better than the network-topology-based allocations; (ii) results from control efficacy for a specific hospital network cannot be generalized to other types of networks. Putting together the global network topology with local factors that drive pathogens transmission, the [Formula: see text]-based allocation method seems to be enough to control of healthcare-associated infections. Overall, the obtained results emphasize the importance of data collection on infection transmission and patient transfers.","PeriodicalId":1,"journal":{"name":"Accounts of Chemical Research","volume":null,"pages":null},"PeriodicalIF":16.4000,"publicationDate":"2023-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Accounts of Chemical Research","FirstCategoryId":"99","ListUrlMain":"https://doi.org/10.1142/s0218339023500262","RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CHEMISTRY, MULTIDISCIPLINARY","Score":null,"Total":0}
引用次数: 0
Abstract
The efficacy of infection prevention and control on several hospital networks is assessed. We tested two kinds of strategy, a network-topology-based allocation and a [Formula: see text]-based allocation, where [Formula: see text] is the basic reproduction number of the infection. For this, a multi-patch deterministic model simulates the spread of carbapenemase-producing Enterobacteriaceae in several theoretical hospital networks parametrized by data from Brazil. Our results show that: (i) the allocation methods based on the [Formula: see text] of the hospitals may work better than the network-topology-based allocations; (ii) results from control efficacy for a specific hospital network cannot be generalized to other types of networks. Putting together the global network topology with local factors that drive pathogens transmission, the [Formula: see text]-based allocation method seems to be enough to control of healthcare-associated infections. Overall, the obtained results emphasize the importance of data collection on infection transmission and patient transfers.
期刊介绍:
Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance.
Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.