The Relationship between LDL Cholesterol Level and Cardiovascular Disease Risk: A Case-Study-Based Cognitive Study

I. Dianat, Seyed Ali Hossein Zahraei
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Abstract

Email: zmohsen14@gmail.com ABSTRACT Cardiovascular disease (CVD) is the leading cause of death globally. High levels of low-density lipoprotein (LDL) cholesterol in the blood have been identified as a significant predictor of CVD risk. This case-studybased cognitive study aimed to investigate the relationship between LDL cholesterol level and CVD risk in a group of 100 patients with CVD. The patients were divided into two groups based on their LDL cholesterol levels: high LDL group (LDL > 130 mg/dL) and normal LDL group (LDL ≤ 130 mg/dL). The medical history of each patient was obtained and analyzed, including factors such as age, gender, smoking history, and family history of CVD. The data were statistically analyzed to investigate the relationship between LDL cholesterol level and the risk of CVD. The results showed that the high LDL group had a significantly higher risk of CVD compared to the normal LDL group (p < 0.05). Age, gender, smoking history, and family history of CVD were also found to be significant risk factors for CVD (p < 0.05). Our study provides evidence for the strong relationship between LDL cholesterol level and CVD risk, which emphasizes the need for personalized and targeted interventions based on individual patient characteristics.
低密度脂蛋白胆固醇水平与心血管疾病风险的关系:一项基于个案研究的认知研究
摘要心血管疾病(CVD)是全球死亡的主要原因。血液中高水平的低密度脂蛋白(LDL)胆固醇已被确定为心血管疾病风险的重要预测因子。这项基于病例研究的认知研究旨在探讨100例CVD患者LDL胆固醇水平与CVD风险之间的关系。根据患者的LDL胆固醇水平分为高LDL组(LDL > 130 mg/dL)和正常LDL组(LDL≤130 mg/dL)。获取并分析每位患者的病史,包括年龄、性别、吸烟史、心血管疾病家族史等因素。对数据进行统计学分析,探讨LDL胆固醇水平与心血管疾病风险的关系。结果显示,高LDL组发生心血管疾病的风险明显高于正常LDL组(p < 0.05)。年龄、性别、吸烟史、CVD家族史也是CVD的重要危险因素(p < 0.05)。我们的研究为低密度脂蛋白胆固醇水平与心血管疾病风险之间的密切关系提供了证据,这强调了基于个体患者特征的个性化和有针对性的干预的必要性。
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