Therapeutic Effect of Multi-Channel Transcranial Direct Current Stimulation (M-tDCS) on Recovery of Cognitive Domains, Motor Functions of Paretic Hand and Gait in Subacute Stroke Survivors-A Randomized Controlled Trial Protocol.

IF 2.9 Q2 NEUROSCIENCES
Neuroscience Insights Pub Date : 2022-03-30 eCollection Date: 2022-01-01 DOI:10.1177/26331055221087741
Midha Divya, Arumugam Narkeesh
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引用次数: 0

Abstract

Background: There has been rapid drift of rehabilitation professionals toward the clinical use of technology aided electrical interventions. Brain is a cortical hub of functionally related neural connections. Motor learning entails strong interaction with the cognitive domains. So better outcomes may be expected by optimally targeting functionally correlated areas simultaneously through tDCS.

Aim: To determine the therapeutic effect of Multi Channel tDCS in combination with Functional electrical stimulation, SaeboFlex and conventional rehabilitation on recovery of Cognitive Domains, Motor Functions of Paretic Hand, and Gait in individuals with subacute Stroke.

Methods: This is prospective, randomized, double blind controlled clinical trial. Subacute Stroke Survivors with the age Group (40-75 years) will constitute the Population of the study. Participants will be randomly allocated to experimental or control group. Participants of Experimental group will receive Multi channel tDCS, Functional electrical stimulation, Saebo Flex Training and conventional rehabilitation. Participants of the group B will receive FES, training with SaeboFlex, conventional physiotherapy intervention similar to as given to the participants of group A and sham multi channel tDCS.

Outcome measures: The primary outcome measures of the study will be Fugl Meyer assessment, Electroencephalogram and secondary outcome measures of the study will be Grip strength, Pinch strength, Nine hole peg test( NHPT), Wisconsin gait scale, Montreal cognitive assessment, Electroencephaloraphy to observe the cortical changes and tDCS adverse effect questionnaire and stroke specific quality of Life scale.

Statistical analysis: The primary analysis of the study will be done at the end of 4 weeks. Statistical analysis of data will be done using SPSS Version 22 with the help of a statistician.

Conclusion: An insight into the therapeutic interventions augmenting, cognitive and motor domains simultaneously may yield better outcomes in the field of stroke rehabilitation thereby improving quality of life of stroke survivors.

多通道经颅直流电刺激(M-tDCS)对亚急性脑卒中幸存者认知域、麻痹手和步态运动功能恢复的疗效——一项随机对照试验方案
背景:康复专业人员迅速转向技术辅助电干预的临床应用。大脑是功能相关神经连接的皮质中枢。运动学习需要与认知领域进行强烈的互动。因此,通过tDCS同时优化靶向功能相关区域可能会获得更好的结果。目的:探讨多通道tDCS联合功能性电刺激、SaeboFlex和常规康复治疗对亚急性脑卒中患者认知域、麻痹性手运动功能和步态恢复的疗效。方法:前瞻性、随机、双盲对照临床试验。亚急性中风幸存者的年龄组(40-75岁)将构成该研究的人群。参与者将被随机分为实验组和对照组。实验组接受多通道tDCS、功能性电刺激、Saebo柔韧性训练和常规康复治疗。B组接受FES、SaeboFlex培训、与A组相似的常规物理治疗干预和假性多通道tDCS。结果测量:本研究的主要结果测量为Fugl Meyer评估、脑电图,次要结果测量为握力、捏紧力、九孔钉试验(NHPT)、威斯康星步态量表、蒙特利尔认知评估、脑电图观察皮质变化、tDCS不良反应问卷和脑卒中特异性生活质量量表。统计分析:在4周结束时对研究进行初步分析。数据的统计分析将在统计学家的帮助下使用SPSS版本22完成。结论:在脑卒中康复领域,同时进行认知和运动领域的治疗干预可能会产生更好的结果,从而提高脑卒中幸存者的生活质量
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Neuroscience Insights
Neuroscience Insights Neuroscience-Neuroscience (all)
CiteScore
6.10
自引率
0.00%
发文量
24
审稿时长
9 weeks
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