Larvicidal, leishmanicidal, insecticidal and anthelmintic effects of Sterculia diversifolia stem bark and leaf

IF 0.9 4区医学 Q4 PHARMACOLOGY & PHARMACY

Bangladesh Journal of Pharmacology Pub Date : 2020-03-10 DOI:10.3329/bjp.v15i1.43235

F. Rabbi, A. Zada, A. Nisar

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引用次数: 8

Abstract

The present study was conducted to evaluate the stem bark and leaf of Sterculia diversifolia for larvicidal, leishmanicidal, insecticidal and anthelmintic activities. In the larvicidal activity, dichloromethane and ethyl acetate fractions of both stem bark and leaf showed significant results, while the ethyl acetate fraction showed mild activity (IC50: 70.09 ± 0.09 μg/mL; 71.25 ± 0.01 μg/mL). In the insecticidal activity of the stem bark, n-hexane fraction showed mild activity (20-40% mortality) against all three subjects, while the insecticidal activity of leaf, methanolic extract and n-hexane fractions showed moderate activity (60% mortality) against Rhyzopertha dominica and Callosobruchus analis. In the anthelmintic activity of stem bark and leaf, ethyl acetate fraction exhibited activity in a dose-dependent manner giving time of paralysis and death shorter followed by dichloromethane fraction with 200 mg/mL concentration. Hence, it is clear that S. diversifolia stem bark and leaf possess larvicidal, leishmanicidal, insecticidal and anthelmintic agents.

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大黄茎皮和叶的杀幼虫、杀利什曼、杀虫和驱虫作用

本研究旨在评价多叶Sterculia diversifolia茎皮和叶的杀幼虫、杀利什曼原虫、杀虫和驱虫活性。在杀幼虫活性方面，茎皮和叶的二氯甲烷和乙酸乙酯组分显示出显著的活性，而乙酸乙酯组份显示出温和的活性（IC50:70.09±0.09μg/mL；71.25±0.01μg/mL）。在茎皮的杀虫活性中，正己烷组分对所有三种受试者都表现出温和的活性（20-40%的死亡率），而叶、甲醇提取物和正己烷组份对稻瘟病菌和安乃馨的杀虫活性表现出中等的活性（60%的死亡率）。在茎皮和叶的驱虫活性中，乙酸乙酯组分表现出剂量依赖性的活性，使麻痹和死亡时间更短，其次是浓度为200mg/mL的二氯甲烷组分。因此，可以清楚地看出，多样叶的茎皮和叶具有杀幼虫、利什曼原虫、杀虫和驱虫剂。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Bangladesh Journal of Pharmacology PHARMACOLOGY & PHARMACY-

CiteScore

1.50

自引率

18.80%

发文量

审稿时长

>12 weeks

期刊介绍： Bangladesh Journal of Pharmacology (Bangladesh J Pharmacol) is an open access, video component, peer-reviewed journal of the Bangladesh Pharmacological Society (BDPS). A scholarly publication is defined ''open access'' when there are no financial, legal or technical barriers to accessing it. Anyone can read, download, copy, distribute, print or use it in educational purpose within the legal agreements. Peer review of a manuscript means the evaluation of research work by one or more people with similar competences. It can be open or blind. We do the single-blind peer review. Our readers want to know the methodology used by the researchers which is very important to get the results. The video clip of one of the methodologies is prepared by the authors and submit it to publish.