Epidemiological Characteristics and Causes of End-stage Renal Disease in Hemodialysis Patients

M. Khazaei, Zainab Eslami Hasan Abadi, Mohammad Keshvari Delavar, M. Shamsizadeh
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引用次数: 3

Abstract

Background and aims: Hemodialysis (HD) is considered as the main method of renal replacement therapy (RRT) for end-stage renal disease (ESRD) patients in many countries including Iran. Given the limited number of epidemiological studies in this regard at the provincial level across the country, the present study aimed to describe the demographic and clinical characteristics of ESRD patients and determine the most important causes of ESRD in Hamadan Province. Methods: This cross-sectional study was conducted on 508 HD patients in Hamadan province in January 2017. The checklist used to gather information comprised of the patient’s demographic and clinical information. The analysis was carried out using descriptive analysis including frequency tables and charts and the chi-square statistic test was used to compare the groups using Stata software, version 12. Results: The prevalence rate of HD treatment was 288.9 per million population (PMP). Further, most under HD patients were married, illiterate, and urban residents. The mean age of patients at the diagnosis was 47.64 ± 15.17 years. Hypertension (37.4%), diabetes (28.74%), and glomerulonephritis (10.63%) were the common causes of ESRD. Eventually, there was a significant difference between ESRD causes according to gender and residency (P < 0.05). Conclusion: In general, the prevalence rate of HD in Hamadan was relatively similar to that of developing countries although it was lower than the national average. Furthermore, hypertension and diabetes were the common causes of ESRD in Hamadan Province. Therefore, preventive strategies should be taken to modify their risk factors.
血液透析患者终末期肾病的流行病学特征及病因分析
背景与目的:在包括伊朗在内的许多国家,血液透析(HD)被认为是终末期肾病(ESRD)患者肾脏替代治疗(RRT)的主要方法。鉴于这方面在全国省级的流行病学研究数量有限,本研究旨在描述哈马丹省ESRD患者的人口学和临床特征,并确定ESRD的最重要原因。方法:对2017年1月在哈马丹省的508例HD患者进行横断面研究。检查表用于收集信息,包括患者的人口统计和临床信息。采用频率表、图表等描述性分析方法进行分析,组间比较采用Stata软件12版卡方统计检验。结果:HD治疗患病率为288.9 /百万人(PMP)。此外,大多数HD患者是已婚、文盲和城市居民。患者平均年龄为47.64±15.17岁。高血压(37.4%)、糖尿病(28.74%)和肾小球肾炎(10.63%)是ESRD的常见病因。最终,不同性别和居住地的ESRD病因差异有统计学意义(P < 0.05)。结论:哈马丹市HD患病率虽低于全国平均水平,但总体上与发展中国家较为接近。此外,高血压和糖尿病是哈马丹省ESRD的常见原因。因此,应采取预防策略,改变其危险因素。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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