An In-vivo Study to Evaluate the Onset of Relief from Ibuprofen, Placebo and Occlusal Splint in Patients with Acute Myalgia in Muscles Related to Temporomandibular Joint: A Comparative Pilot Study

D. Gupta, N. Nirmal, Himanshu Arora, Sonal S. Mehta, Jishnu S., Ruchi Raj
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Abstract

Purpose: The treatment priority in management of Temporomandibular Joint (TMJ) pain is directed towards the causative factor along with symptomatic treatment. In this process many times psychological aspect is overlooked. Hence with this pilot study, importance of psychological aspect of Temporomandibular Joint Disorder (TMD) is emphasised. Methods and Material: 15 patients suffering from pain in TMD region who qualify under myalgia pain in DC/TMD Axis I category were selected. Patients were divided into 3 groups; Ibuprofen, placebo and occlusal splint with 5 patients in each group. Pain assessment was done at the first visit, 7th day visit and 14th day visit using a VAS scale. Statistical Analysis Used: Friedman Test was applied to determine overall relief from pain in the three groups. Wilcoxon sign rank test evaluated pain relief between each time interval. Kruskal Wallis Test compared different groups for relief from pain at each time interval. Key Finding: Wilcoxon sign rank test showed a significant pain relief in all three groups from I day to I follow up day and I day to II follow up day. However Pain relief from I follow up to II follow up day was significant only in placebo group. Conclusions: Management of TMD myalgia requires a comprehensive understanding of physical and psychological aspect. This will aid us in formulating a treatment plan comprising pharmacotherapy, placebo or physical therapy or combination of any of these.
一项评估布洛芬、安慰剂和咬合夹板对颞下颌关节相关肌肉急性肌痛患者的缓解作用的体内研究:一项比较试点研究
目的:颞下颌关节(TMJ)疼痛的治疗优先考虑病因和对症治疗。在这个过程中,很多时候心理方面被忽视了。因此,这项初步研究强调了颞下颌关节紊乱病(TMD)心理方面的重要性。方法和材料:选择15例TMD区疼痛患者,符合DC/TMD轴I类肌痛。将患者分为3组;布洛芬、安慰剂和咬合夹板,每组5名患者。在第一次就诊、第7天就诊和第14天就诊时使用VAS量表进行疼痛评估。使用的统计分析:应用Friedman检验来确定三组患者的疼痛总体缓解情况。Wilcoxon征秩检验评估了每个时间间隔之间的疼痛缓解情况。Kruskal-Wallis测试比较了不同组在每个时间间隔的疼痛缓解情况。关键发现:Wilcoxon征秩检验显示,从第I天到第I天随访以及从第I天到第II天随访,所有三组的疼痛都有显著缓解。然而,从第一次随访到第二次随访的疼痛缓解仅在安慰剂组中显著。结论:TMD肌痛的治疗需要对生理和心理方面有全面的了解。这将有助于我们制定包括药物治疗、安慰剂或物理治疗或其中任何一种组合的治疗计划。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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