Liquid-Phase Transmission Electron Microscopy for Reliable In Situ Imaging of Nanomaterials.

IF 7.6 2区工程技术 Q1 CHEMISTRY, APPLIED

Annual review of chemical and biomolecular engineering Pub Date : 2022-06-10 DOI:10.1146/annurev-chembioeng-092120-034534

Jongbaek Sung, Yuna Bae, Hayoung Park, Sungsu Kang, Back Kyu Choi, Joodeok Kim, Jungwon Park

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引用次数: 5

Abstract

Liquid-phase transmission electron microscopy (LPTEM) is a powerful in situ visualization technique for directly characterizing nanomaterials in the liquid state. Despite its successful application in many fields, several challenges remain in achieving more accurate and reliable observations. We present LPTEM in chemical and biological applications, including studies for the morphological transformation and dynamics of nanoparticles, battery systems, catalysis, biomolecules, and organic systems. We describe the possible interactions and effects of the electron beam on specimens during observation and present sample-specific approaches to mitigate and control these electron-beam effects. We provide recent advances in achieving atomic-level resolution for liquid-phase investigation of structures anddynamics. Moreover, we discuss the development of liquid cell platforms and the introduction of machine-learning data processing for quantitative and objective LPTEM analysis.

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用于纳米材料可靠原位成像的液相透射电子显微镜。

液相透射电子显微镜(ltem)是一种强大的原位可视化技术，可以直接表征纳米材料的液态。尽管它在许多领域得到了成功的应用，但在获得更准确和可靠的观测结果方面仍然存在一些挑战。我们介绍了LPTEM在化学和生物学上的应用，包括纳米颗粒、电池系统、催化、生物分子和有机系统的形态转化和动力学研究。我们描述了在观察过程中电子束对样品可能的相互作用和影响，并提出了特定样品的方法来减轻和控制这些电子束效应。我们提供了在液相结构和动力学研究中实现原子级分辨率的最新进展。此外，我们还讨论了液细胞平台的发展以及引入定量和客观的LPTEM分析的机器学习数据处理。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Annual review of chemical and biomolecular engineering CHEMISTRY, APPLIED-ENGINEERING, CHEMICAL

CiteScore

16.00

自引率

0.00%

发文量

期刊介绍： The Annual Review of Chemical and Biomolecular Engineering aims to provide a perspective on the broad field of chemical (and related) engineering. The journal draws from disciplines as diverse as biology, physics, and engineering, with development of chemical products and processes as the unifying theme.