Analysis of dosimetric properties in the field of radiotherapy of glucose irradiated by megavoltage X photons, electrons and analyzed by EPR spectroscopy

Perspectives in science Pub Date : 2019-09-01 DOI:10.1016/j.pisc.2019.100396

Redouane El Baydaoui , Mohammed Mikou , Mustapha Bougteb , Mohammed Reda Mesradi

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Abstract

In this work, we propose to analyze the dosimetric properties of the glucose Electron Paramagnetic Resonance (EPR) system. This study consists of irradiating samples of glucose by megavoltage X photons and electrons delivered by a particle accelerator used in radiotherapy. After irradiation, the samples were analyzed by EPR. The measurements obtained on samples placed at different depth in a phantom of PolyMethyl Methacrylate “PMMA” have firstly identified the depths corresponding to the maximum dose deposition for both particles and samples used. Analysis by EPR showed that the threshold measurable dose for this dosimetric system is about 2 Gy. The variation of curves obtained from the peak-to-peak EPR intensity, or the results of the double integration of the spectrum as a function of the irradiation dose, are linear with a correlation coefficient exceeding 0.999. Glucose seems slightly more sensitive to megavoltage X photons than megavoltage electrons. The results reveal interesting potential dosimetry of the glucose/EPR system in the field of radiation therapy.

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巨压X光子、电子辐照葡萄糖放射领域的剂量学特性分析及EPR光谱分析

在这项工作中，我们建议分析葡萄糖电子顺磁共振(EPR)系统的剂量学性质。这项研究包括用放射治疗中使用的粒子加速器传递的兆伏X光子和电子照射葡萄糖样品。辐照后对样品进行EPR分析。对放置在聚甲基丙烯酸甲酯“PMMA”模体中不同深度的样品进行的测量首次确定了所使用颗粒和样品的最大剂量沉积所对应的深度。EPR分析表明，该剂量学体系的阈值可测剂量约为2gy。峰间EPR强度曲线的变化，即光谱作为辐照剂量函数的二重积分曲线的变化，均为线性变化，相关系数超过0.999。葡萄糖似乎对超电压X光子比超电压电子更敏感。结果揭示了葡萄糖/EPR系统在放射治疗领域有趣的潜在剂量学。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Perspectives in science

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