{"title":"DraggleSimulator: An Open Source Web Application for Teaching Genetic Drift","authors":"Mark Fisher","doi":"10.21105/jose.00070","DOIUrl":null,"url":null,"abstract":"The concept of genetic drift in population genetics is a notoriously difficult concept to teach and to learn. DraggleSimulator is an open-source simulation web application written using Google’s Angular framework that allows students to create a metapopulation (a collection of isolated subpopulations) of draggles: fictitious, diploid (meaning they have a mom and a dad and two copies of every gene in their genomes, just like humans), monogamous (only mating with one other individual), and simultaneously-hermaphroditic animals (any individual can mate with any other individual and the sex of the individual is a non-issue). The animals mate at a rate consistent with replacement-level fertility (2 offspring per couple), and the simulator tracks these matings and how they change the composition of alleles (versions of genes) across generations.","PeriodicalId":75094,"journal":{"name":"The Journal of open source education","volume":" ","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2019-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"The Journal of open source education","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.21105/jose.00070","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
The concept of genetic drift in population genetics is a notoriously difficult concept to teach and to learn. DraggleSimulator is an open-source simulation web application written using Google’s Angular framework that allows students to create a metapopulation (a collection of isolated subpopulations) of draggles: fictitious, diploid (meaning they have a mom and a dad and two copies of every gene in their genomes, just like humans), monogamous (only mating with one other individual), and simultaneously-hermaphroditic animals (any individual can mate with any other individual and the sex of the individual is a non-issue). The animals mate at a rate consistent with replacement-level fertility (2 offspring per couple), and the simulator tracks these matings and how they change the composition of alleles (versions of genes) across generations.