DraggleSimulator: An Open Source Web Application for Teaching Genetic Drift

Mark Fisher
{"title":"DraggleSimulator: An Open Source Web Application for Teaching Genetic Drift","authors":"Mark Fisher","doi":"10.21105/jose.00070","DOIUrl":null,"url":null,"abstract":"The concept of genetic drift in population genetics is a notoriously difficult concept to teach and to learn. DraggleSimulator is an open-source simulation web application written using Google’s Angular framework that allows students to create a metapopulation (a collection of isolated subpopulations) of draggles: fictitious, diploid (meaning they have a mom and a dad and two copies of every gene in their genomes, just like humans), monogamous (only mating with one other individual), and simultaneously-hermaphroditic animals (any individual can mate with any other individual and the sex of the individual is a non-issue). The animals mate at a rate consistent with replacement-level fertility (2 offspring per couple), and the simulator tracks these matings and how they change the composition of alleles (versions of genes) across generations.","PeriodicalId":75094,"journal":{"name":"The Journal of open source education","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2019-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"The Journal of open source education","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.21105/jose.00070","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0

Abstract

The concept of genetic drift in population genetics is a notoriously difficult concept to teach and to learn. DraggleSimulator is an open-source simulation web application written using Google’s Angular framework that allows students to create a metapopulation (a collection of isolated subpopulations) of draggles: fictitious, diploid (meaning they have a mom and a dad and two copies of every gene in their genomes, just like humans), monogamous (only mating with one other individual), and simultaneously-hermaphroditic animals (any individual can mate with any other individual and the sex of the individual is a non-issue). The animals mate at a rate consistent with replacement-level fertility (2 offspring per couple), and the simulator tracks these matings and how they change the composition of alleles (versions of genes) across generations.
DraggleSimulator:一个用于遗传漂移教学的开源Web应用程序
在群体遗传学中,遗传漂变的概念是一个非常难教难学的概念。DraggleSimulator是一个使用谷歌的Angular框架编写的开源模拟web应用程序,它允许学生创建一个draggles元种群(一个孤立的子种群的集合):虚构的,二倍体(意味着它们有一个妈妈和一个爸爸,基因组中的每个基因都有两个副本,就像人类一样),一夫一妻制(只与另一个个体交配),同时雌雄同体动物(任何个体都可以与任何其他个体交配,个体的性别无关)。这些动物的交配速度与替代水平的生育率一致(每对夫妇生育2个后代),模拟器跟踪这些交配以及它们如何在几代之间改变等位基因(基因的版本)的组成。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
自引率
0.00%
发文量
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信