{"title":"Synthesis of trans-diamide derivatives from fumaryl chloride and determination of DPPH scavenging activity of synthesized molecules","authors":"Ö. Yılmaz","doi":"10.18596/jotcsa.627805","DOIUrl":null,"url":null,"abstract":"In this work, new trans-diamide derivatives were synthesized with the reaction between fumaryl chloride and substituted anilines. After successful synthesis of trans-amides, antioxidant activity of all synthesized molecules was investigated via DPPH method and calculated IC50 values. All trans-amides were characterized by 1H-NMR, 13C-NMR, 19F-NMR, GC-MS and FTIR spectroscopic techniques.","PeriodicalId":17402,"journal":{"name":"Journal of the Turkish Chemical Society, Section A: Chemistry","volume":"7 1","pages":"143-150"},"PeriodicalIF":0.0000,"publicationDate":"2019-11-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"2","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of the Turkish Chemical Society, Section A: Chemistry","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.18596/jotcsa.627805","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"Chemistry","Score":null,"Total":0}
引用次数: 2
Abstract
In this work, new trans-diamide derivatives were synthesized with the reaction between fumaryl chloride and substituted anilines. After successful synthesis of trans-amides, antioxidant activity of all synthesized molecules was investigated via DPPH method and calculated IC50 values. All trans-amides were characterized by 1H-NMR, 13C-NMR, 19F-NMR, GC-MS and FTIR spectroscopic techniques.