Extracellular vesicles as novel therapeutic targets and diagnosis markers

Extracellular vesicle Pub Date : 2022-12-01 DOI:10.1016/j.vesic.2022.100017

Yu Zhang , Weiliang Wu , Xiangbin Pan , Yanli Wang , Chengjie Wu , Lin Lu , Xi-Yong Yu , Yangxin Li

引用次数: 1

Abstract

Extracellular vesicles (EVs) are membranous vesicles secreted from cells to the outside and are widely present in body fluids. The most commonly used method to isolate EVs is ultracentrifugation. EVs contain lipids, proteins, genetic material, and organelles, which can be used as communication carriers between different cells and potential disease biomarkers. EVs secreted by different cells (cancer cells, adipocytes, mesenchymal stem cells, immune cells et al.) play different functions. With the development of technology, EVs can also be engineered to deliver drugs. EVs also play an important role in the progression, prevention, diagnosis, and treatment of Corona Virus Disease 2019 (COVID-19).

查看原文本刊更多论文

细胞外囊泡作为新的治疗靶点和诊断标志物

细胞外囊泡(EVs)是由细胞向外分泌的膜状囊泡，广泛存在于体液中。最常用的分离ev的方法是超离心。电动汽车含有脂质、蛋白质、遗传物质和细胞器，可作为不同细胞之间的通讯载体和潜在的疾病生物标志物。不同细胞(癌细胞、脂肪细胞、间充质干细胞、免疫细胞等)分泌的ev具有不同的功能。随着技术的发展，电动汽车也可以用于运送药物。电动汽车在2019冠状病毒病(COVID-19)的进展、预防、诊断和治疗中也发挥着重要作用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Extracellular vesicle Biochemistry, Genetics and Molecular Biology (General)

自引率

0.00%

发文量

审稿时长

43 days