Escala Barcelona para la apraxia bucofonatoria: instrumento de evaluación cuantitativo

IF 3.1 4区医学 Q2 CLINICAL NEUROLOGY

Neurologia Pub Date : 2025-01-01 DOI:10.1016/j.nrl.2022.09.003

N. Montagut , S. Borrego-Écija , J. Herrero , A. Lladó , M. Balasa , E. Muñoz , F. Valldeoriola , R. Sánchez-Valle

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引用次数: 0

Abstract

Introduction

Currently there is no tool to quantify buccophonatory apraxia to stratify, compare and monitor patients longitudinally in an objective manner. Our aim in this study is to create a quantitative scale for buccophonatory apraxia and evaluate it in patients with the non-fluent/grammatical variant of Primary Progressive Aphasia (nfvPPA) and other neurodegenerative diseases that occur with speech and/or language problems.

Methods

The scale was designed based on useful elements in the assessment of buccophonatory apraxia and the total was quantified in seconds. The scale was administered to 64 participants with diagnoses of: nfvPPA, semantic variant of Primary Progressive Aphasia (svPPA), logopenic variant of Primary Progressive Aphasia (lvPPA), Huntington's disease, Parkinson's disease, as well as a group of healthy controls.

Results

Patients showed a significantly higher score compared to controls. The group nfvPPA had the highest mean score on the scale (429 seconds ± 278). The scale was useful to differentiate vnfPPA from svPPA and Parkinson's disease (area under curve [AUC] of 0.956 and 0.989 respectively), but less to differentiate it from Huntington's disease (AUC = 0.67) and lvPPA. There was a statistically significant relationship between total score and disease severity in nfvPPA (p < 0.029).

Conclusions

The Barcelona scale for buccophonatory apraxia could be useful to quantitatively evaluate buccophonatory apraxia in different neurodegenerative diseases, and compare patients, especially in nfvPPA.

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目前还没有一种量化工具来客观地对患者进行分层、比较和纵向监测。本研究的目的是为原发性进行性失语症（nfvPPA）的非流利/语法变体和其他伴有言语和/或语言问题的神经退行性疾病患者创建一个喉音失用症的定量量表，并对其进行评估。方法根据嗓音失用症评估中有用的要素设计量表，以秒为单位对总分进行量化。该量表被用于64名被诊断为：nfvPPA、原发性进行性失语症语义变体（svPPA）、原发性进行性失语症语义变体（lvPPA）、亨廷顿病、帕金森病以及一组健康对照组的参与者。结果与对照组相比，患者得分明显高于对照组。nfvPPA组的平均评分最高（429秒±278）。该量表用于区分vnfPPA与svPPA、帕金森病（曲线下面积[AUC]分别为0.956、0.989），但用于区分亨廷顿病（AUC = 0.67）、lvPPA的效果较差。nfvPPA总分与疾病严重程度有统计学意义(p <；0.029)。结论巴塞罗那声带失用症量表可定量评价不同神经退行性疾病患者的声带失用症，并对不同患者进行比较，尤其是nfvPPA患者。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Neurologia 医学-临床神经学

CiteScore

5.90

自引率

2.60%

发文量

135

审稿时长

48 days

期刊介绍： Neurología es la revista oficial de la Sociedad Española de Neurología y publica, desde 1986 contribuciones científicas en el campo de la neurología clínica y experimental. Los contenidos de Neurología abarcan desde la neuroepidemiología, la clínica neurológica, la gestión y asistencia neurológica y la terapéutica, a la investigación básica en neurociencias aplicada a la neurología. Las áreas temáticas de la revistas incluyen la neurologia infantil, la neuropsicología, la neurorehabilitación y la neurogeriatría. Los artículos publicados en Neurología siguen un proceso de revisión por doble ciego a fin de que los trabajos sean seleccionados atendiendo a su calidad, originalidad e interés y así estén sometidos a un proceso de mejora. El formato de artículos incluye Editoriales, Originales, Revisiones y Cartas al Editor, Neurología es el vehículo de información científica de reconocida calidad en profesionales interesados en la neurología que utilizan el español, como demuestra su inclusión en los más prestigiosos y selectivos índices bibliográficos del mundo.