Dengue and Viral Circulation in Infected Cases of Ahmedabad: A Single Centre Study

Q2 Social Sciences
Parth Shah, Nidhi D. Shah, Ayushi S. Patel, Siddhi M. Kurtadikar, H. Dixit, K. Patel, S. Murarka, Bhavini S. Shah, M. V. Rao
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引用次数: 2

Abstract

ABSTRACT The dengue fever is a debilitating arthropod-borne disease caused by one of the four closely related dengue viruses. The symptoms appear 3 – 14 days after mosquito bite and range from mild fever to very high fever. Based on these symptoms, a total of 178 referral cases were analyzed. Patients were asked to fill out a consent form which was followed by blood collection. Parameters that were analyzed amongst these patients include: Platelet count, transaminases, Dengue Real Time-PCR detection, gel-based dengue serotyping. An overall 12.36 percent (22/178) prevalence of dengue infection was detected in the post-monsoon season that is from October 201 6 to March 2017. Younger age groups of males were more affected (18.2%) amongst all groups. Patients who tested positive for dengue had markedly reduced platelet counts as compared to those of negative control cases. Altered serum glutamic oxaloacetic transaminase (SGOT) levels were also observed amongst patients with infection leading to liver dysfunction. The most common serotype prevalent was DENV-3 (45%), followed by DENV-4 (36%) and then DENV-2 (18%). No prevalence of DENV-1 was found. In the absence of targeted vaccination and medication for dengue fever, it is essential to study the epidemiology of it for controlling the spread of dengue during post-monsoon season.
艾哈迈达巴德感染病例中的登革热和病毒传播:一项单中心研究
登革热是由四种密切相关的登革热病毒之一引起的一种节肢动物传播疾病。症状在蚊子叮咬后3 - 14天出现,由低烧到高烧不等。基于这些症状,对178例转诊病例进行分析。患者被要求填写一份同意书,然后进行采血。在这些患者中分析的参数包括:血小板计数、转氨酶、登革热Real - Time-PCR检测、凝胶型登革热血清分型。在2016年10月至2017年3月的季风后季节,发现登革热感染的总体流行率为12.36%(22/178)。在所有年龄组中,年龄较小的男性受影响更大(18.2%)。与阴性对照病例相比,登革热检测呈阳性的患者血小板计数明显减少。血清谷草转氨酶(SGOT)水平在感染导致肝功能障碍的患者中也观察到改变。最常见的血清型是DENV-3(45%),其次是DENV-4(36%),然后是DENV-2(18%)。未发现DENV-1的流行。在缺乏针对登革热的有针对性的疫苗接种和药物治疗的情况下,研究登革热的流行病学对于控制登革热在后季风季节的传播至关重要。
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来源期刊
Studies on Ethno-Medicine
Studies on Ethno-Medicine Social Sciences-Cultural Studies
CiteScore
0.50
自引率
0.00%
发文量
13
期刊介绍: Studies on Ethno-Medicine is a peer reviewed, internationally circulated journal. It publishes reports of original research, theoretical articles, timely reviews, brief communications, book reviews and other publications in the interdisciplinary field of ethno-medicine. The journal serves as a forum for physical, social and life scientists as well as for health professionals. The transdisciplinary areas covered by this journal include, but are not limited to, Physical Sciences, Anthropology, Sociology, Geography, Life Sciences, Environmental Sciences, Botany, Agriculture, Home Science, Zoology, Genetics, Biology, Medical Sciences, Public Health, Demography and Epidemiology. The journal publishes basic, applied and methodologically oriented research from all such areas. The journal is committed to prompt review, and priority publication is given to manuscripts with novel or timely findings, and to manuscript of unusual interest. Further, the manuscripts are categorised under three types, namely - Regular articles, Short Communications and Reviews. The researchers are invited to submit original papers in English (papers published elsewhere or under consideration elsewhere shall not be considered).
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