Propiedad antibacteriana de un extracto de semilla de Mangifera indica L. sobre Staphylococcus aureus resistente a la meticilina

Nirza Noguera Machado, J. Trejo, Libia Torres, P. Valera, Rosmina Visconti, N. Zambrano, Franklin Jesús Pacheco Coello, M. Mendez, Luis Ojeda
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Abstract

The “mango” tree (Mangifera indica L.) have been use in traditional medicine for the treatmentof different ailments. Is a known that diversity extracts of various parts plants have activitymicroorganism pathogenic. In this work were investigated the antimicrobial activity of mangoseeds extract against Staphylococcus aureus methicillin-resistant strains (MRSA) 1025 and 1920. Theseeds extractions prepared by maceration whit ethanol 90%. The phytochemical constituents ofextracts were characterized for total phenol content (TPC) and total flavonoids (TF). Antibacterialactivity of extracts were determined using disk diffusion, agar dilution methods. The resultsshowed that the seeds extracts contents higher to TPC (85.60 ± 2.13 mg EAG/g of extract) and TF(49.32 ± 1.12 mg CE/g of extract). The result revealed that the extracts possess good antibacterialactivity against S. aureus MRSA 1025 and 1920, the inhibition zones ranged from 6.0 mm to 19 mm,at different concentration extracts probed. The results probed that the mango seed extract containedmany compounds such as phenolic that could be affect bacteria S. aureus MRSA, and these bioactivecompounds to be isolated for the production of new antibiotics.
芒果种子提取物对甲氧西林耐药金黄色葡萄球菌的抗菌特性
芒果树(Mangifera indica L.)在传统医学中被用来治疗不同的疾病。众所周知,植物各部位的多样性提取物具有活性微生物致病性。研究了芒果籽提取物对耐甲氧西林金黄色葡萄球菌(MRSA) 1025和1920的抑菌活性。浸渍制备的种子提取液中乙醇含量为90%。以总酚含量(TPC)和总黄酮含量(TF)对提取物的植物化学成分进行了表征。采用圆盘扩散法、琼脂稀释法测定提取物的抑菌活性。结果表明,种子提取物的TPC(85.60±2.13 mg EAG/g)和TF(49.32±1.12 mg CE/g)含量较高。结果表明,提取物对金黄色葡萄球菌MRSA 1025和1920具有良好的抑菌活性,不同浓度提取物对金黄色葡萄球菌MRSA 1025和1920的抑制范围在6.0 ~ 19 mm之间。结果表明,芒果籽提取物中含有多种可影响金黄色葡萄球菌MRSA的化合物,如酚类化合物,这些生物活性化合物可用于生产新的抗生素。
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