The correlation between the embryological development of the pancreas and the local extent of the pancreatic tumors

Abstract

Progression reported so far in the field of hepato-bilio-pancreatic surgery leaded to a significant increase of the number of cases diagnosed with borderline or locally advanced pancreatic tumors which are successfully submitted to radical surgery. However, it has been observed that local invasion of the vascular structures respects the embryological and anatomical development of the pancreatic parenchyma. The aim of the current paper is to analyze the correlation ship between the embryological development of the pancreas, location, extent and possible therapeutic strategies in borderline or locally advanced pancreatic head cancer.