D. Hermanto, N. Ismillayli, Irmawanti Irmawanti, Ilfa Fathulloh, Diska Nila, U. K. Zuryati, H. Muliasari, R. Wirawan
{"title":"Electrochemically Synthesized Biogenic Silver Nanoparticles Using Green Tea Extract as a Promising Antioxidant","authors":"D. Hermanto, N. Ismillayli, Irmawanti Irmawanti, Ilfa Fathulloh, Diska Nila, U. K. Zuryati, H. Muliasari, R. Wirawan","doi":"10.33640/2405-609x.3276","DOIUrl":null,"url":null,"abstract":"Abstract The role of an antioxidant in cancer prevention has led to the development of its synthesis, including green tea-capped silver nanoparticles (AgNPs), which are natural antioxidants. The biogenic AgNPs were synthesized electrochemically from pure silver wire using local green tea extract for the first time, with a characteristic peak at 420 nm. The method shortened the reaction time and produced long-term stable and narrow-size distribution nanoparticles. The spherical AgNP with an average size of ~17 nm was confirmed in TEM analysis. Furthermore, FTIR analysis and phytochemical assays revealed that the -OH group of flavonoids and terpenoids was responsible for the process. The DPPH method confirmed the higher antioxidant activity of AgNPs than extract, with an IC50 of 54.99 ppm. Hence, the method can be implemented for the large-scale production of pharmaceutical products in treating harmful diseases.","PeriodicalId":17782,"journal":{"name":"Karbala International Journal of Modern Science","volume":" ","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2023-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"2","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Karbala International Journal of Modern Science","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.33640/2405-609x.3276","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 2
Abstract
Abstract The role of an antioxidant in cancer prevention has led to the development of its synthesis, including green tea-capped silver nanoparticles (AgNPs), which are natural antioxidants. The biogenic AgNPs were synthesized electrochemically from pure silver wire using local green tea extract for the first time, with a characteristic peak at 420 nm. The method shortened the reaction time and produced long-term stable and narrow-size distribution nanoparticles. The spherical AgNP with an average size of ~17 nm was confirmed in TEM analysis. Furthermore, FTIR analysis and phytochemical assays revealed that the -OH group of flavonoids and terpenoids was responsible for the process. The DPPH method confirmed the higher antioxidant activity of AgNPs than extract, with an IC50 of 54.99 ppm. Hence, the method can be implemented for the large-scale production of pharmaceutical products in treating harmful diseases.