Efficacy with Autologous Conjunctival Implant Associated with Phototherapeutic Keratectomy (PTK) in the Treatment of the Pterygium

P. Fiorini, A. Mularoni, L. Di Silvestre, L. Inferrera, P. Aragona, A. Meduri
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引用次数: 1

Abstract

Purpose: To evaluate the efficacy of new formula of the PTK calculated with the head-limbus-distance (=height) and limbal base length of the pterygium and ablation thickness on the anterior corneal curvature and visual acuity, associated with autologous conjuntival implant in patients with primary (Group A)and secondary(Group B) pterygium. Setting: This study was developed in the Department of Ophthalmology, Maggiore Hospital of Bologna. Design: Prospective non randomized study was conducted in 18 eyes of 18 subjects (9 eyes primary and 9 eyes with recurrent pterygium) operated with a dedicated PTK program. Methods: All patients signed informed consent before the start of the research. BCVA (Best Corrected Visual Acuity), mean refractive error (ME) and topographic astigmatism and recurrence of pterygium was followed. Mean follow up was 18.67 ± 6.13 months Min: 12 Max: 24 months. Results: Mean post-operative BCVA increased at 3-24 months compared with pre-op BCVA (p= 0.003). Mean post-op BCVA improved independent of the optical zone involvement in the pre-op (p= 0.845). Mean Pre-op astigmatism (Group A): was: 0,97 ± 2,7 (MIN: -2,8 Max: +5). Mean pre-op Astigmatism (Group B) :-0,33 ± 1,98 (MIN: -3 Max:+4). Astigmatism reduction in the group A: 0 D; Group B: -0,1D ± 0,74D MIN: -1 Max: +1. No statistically difference at 24 months from two groups in BCVA (p=0,59), Sf ( P=0,7), ME(p=0,7), astigmatism ( p=0,96) ANOVA. Recurrence of pterygium was: 0%. Conclusions: The dedicated programme of PTK was shown to be safe and effective for the treatment of the pterygium. BCVA can be improved by providing a smooth corneal surface in cases of optical zone involvement. 
自体结膜植入联合光疗性角膜切除术治疗翼状胬肉的疗效观察
目的:评价以翼状胬肉的头缘距离(=高度)和角膜缘基部长度以及消融厚度计算的PTK新公式对原发性(A组)和继发性(B组)翼状胬肉患者自体结膜植入术后角膜前曲率和视力的影响。背景:本研究在博洛尼亚马焦雷医院眼科进行。设计:对18名受试者中的18只眼(9只眼为原发性翼状胬肉,9只眼为复发性翼状胬肉)进行前瞻性非随机研究。方法:所有患者在研究开始前签署知情同意书。随访BCVA(最佳矫正视力)、平均屈光不正(ME)、地形散光和翼状胬肉复发。平均随访时间为18.67±6.13个月,最小12个月,最大24个月。结果:与术前相比,术后3-24个月的平均BCVA增加(p=0.003)。术后平均BCVA改善与术前光学区无关(p=0.845)。术前平均散光(A组)为:0.97±2.7(最小值:-2.8最大值:+5)。术前平均散光(B组):-0.33±1.98(最小值:-3最大值:+4)。A组散光减少:0 D;B组:-0.1D±0.74D最小值:-1最大值:+1。24个月时,两组的BCVA(p=0.59)、Sf(p=0.7)、ME(p=0.75)、散光(p=0.96)ANOVA无统计学差异。翼状胬肉复发率为0%。结论:PTK治疗翼状胬肉安全有效。BCVA可以通过在光学区受累的情况下提供平滑的角膜表面来改善。
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